Literature DB >> 1466876

Pergolide can induce soluble superoxide dismutase in rat striata.

A Clow1, T Hussain, V Glover, M Sandler, M Walker, D Dexter.   

Abstract

Pergolide, a dopamine receptor agonist, given daily i.p. for three weeks at 0.04 mg/kg and 0.4 mg/kg, significantly induced soluble (Cu-Zn) superoxide dismutase in the rat striatum, while having no effect on the mitochondrial (Mn) form of the enzyme. Such induction, which can also be effected by (-)-deprenyl, may help to protect against nigrostriatal degeneration.

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Year:  1992        PMID： 1466876     DOI： 10.1007/bf01250515

Source DB:  PubMed          Journal:  J Neural Transm Gen Sect


  19 in total

1.  Anxiogenic activity of isatin, a putative biological factor, in rodents.

Authors:  S K Bhattacharya; S K Mitra; S B Acharya
Journal:  J Psychopharmacol       Date:  1991-01       Impact factor: 4.153

2.  Effect of deprenyl on the progression of disability in early Parkinson's disease.

Authors: 
Journal:  N Engl J Med       Date:  1989-11-16       Impact factor: 91.245

3.  Maintenance on L-deprenyl prolongs life in aged male rats.

Authors:  N W Milgram; R J Racine; P Nellis; A Mendonca; G O Ivy
Journal:  Life Sci       Date:  1990       Impact factor: 5.037

4.  Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species.

Authors:  J M Tolmasoff; T Ono; R G Cutler
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

5.  The effect of deprenyl (selegiline) on the natural history of Parkinson's disease.

Authors:  J W Tetrud; J W Langston
Journal:  Science       Date:  1989-08-04       Impact factor: 47.728

6.  Chronic dietary pergolide preserves nigrostriatal neuronal integrity in aged-Fischer-344 rats.

Authors:  D L Felten; S Y Felten; R W Fuller; T D Romano; E B Smalstig; D T Wong; J A Clemens
Journal:  Neurobiol Aging       Date:  1992 Mar-Apr       Impact factor: 4.673

7.  Superoxide dismutase partially prevents sympathetic denervation by 6-hydroxydopamine.

Authors:  A Albino-Teixeira; I Azevedo; F Martel; W Osswald
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-07       Impact factor: 3.000

8.  The striatal dopamine dependency of life span in male rats. Longevity study with (-)deprenyl.

Authors:  J Knoll
Journal:  Mech Ageing Dev       Date:  1988-12       Impact factor: 5.432

9.  Isatin: identity with the purified endogenous monoamine oxidase inhibitor tribulin.

Authors:  V Glover; J M Halket; P J Watkins; A Clow; B L Goodwin; M Sandler
Journal:  J Neurochem       Date:  1988-08       Impact factor: 5.372

Review 10.  Pergolide: a dopamine agonist at both D1 and D2 receptors.

Authors:  R W Fuller; J A Clemens
Journal:  Life Sci       Date:  1991       Impact factor: 5.037
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  4 in total

1.  Effect of pergolide on endogenous and exogenous L-DOPA metabolism in the rat striatum: a microdialysis study.

Authors:  S Dethy; M A Laute; A Luxen; J Hildebrand; S Goldman
Journal:  J Neural Transm Gen Sect       Date:  1995

Review 2.  New directions in the drug treatment of Parkinson's disease.

Authors:  J L Montastruc; O Rascol; J M Senard
Journal:  Drugs Aging       Date:  1996-09       Impact factor: 3.923

3.  Dopamine agonist 3-PPP fails to protect against MPTP-induced toxicity.

Authors:  Dhanasekaran Muralikrishnan; Manuchair Ebadi; Holly M Brown-Borg
Journal:  Neurochem Res       Date:  2004-02       Impact factor: 3.996

Review 4.  Clinical pharmacology of dopamine agonists in Parkinson's disease.

Authors:  K W Lange
Journal:  Drugs Aging       Date:  1998-11       Impact factor: 4.271
  4 in total

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