Literature DB >> 1466748

PCR-based analysis of the TCR repertoire in human autoimmune diseases.

C Marguerie1, C Lunardi, A So.   

Abstract

Characterization of T cells at sites of autoimmune damage has been difficult. Now, however, polymerase chain reaction (PCR)-based methods are being used to analyse T-cell receptor (TCR) gene expression in such lesions. Here, Christopher Marguerie, Claudio Lunardi and Alex So summarize and interpret the most recent findings and describe the current understanding of TCR usage in autoimmune diseases.

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Year:  1992        PMID： 1466748     DOI： 10.1016/0167-5699(92)90166-5

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  13 in total

1.  Increased expression of V beta 1.2 T cells in the cerebrospinal fluid of patients with multiple sclerosis.

Authors:  O Perrella; M Perrella; A D'Antonio; P B Carrieri
Journal:  Ital J Neurol Sci       Date:  1996-12

2.  Population study of T cell receptor V beta gene usage in peripheral blood lymphocytes: differences in ethnic groups.

Authors:  A Geursen; M A Skinner; L A Townsend; L K Perko; S J Farmiloe; J S Peake; I J Simpson; J D Fraser; P L Tan
Journal:  Clin Exp Immunol       Date:  1993-10       Impact factor: 4.330

3.  T cell receptor genetics, autoimmunity and asthma.

Authors:  A J Frew; J Dasmahapatra
Journal:  Thorax       Date:  1995-09       Impact factor: 9.139

4.  T cell receptor V-gene usage in oral lichen planus; increased frequency of T cell receptors expressing V alpha 2 and V beta 3.

Authors:  C Simark-Mattsson; G Bergenholtz; M Jontell; A Tarkowski; U I Dahlgren
Journal:  Clin Exp Immunol       Date:  1994-12       Impact factor: 4.330

5.  Heterogeneity of rearranged T cell receptor V alpha and V beta gene transcripts in synovial fluid T cells of HLA-B27 positive reactive arthritis patients.

Authors:  G M Verjans; V N Klaren; M Leirisalo-Repo; J H Ringrose; H Repo; A Steinle; C E Van Doornik; T E Feltkamp
Journal:  Clin Rheumatol       Date:  1996-01       Impact factor: 2.980

Review 6.  Diagnostic role of tests for T cell receptor (TCR) genes.

Authors:  E Hodges; M T Krishna; C Pickard; J L Smith
Journal:  J Clin Pathol       Date:  2003-01       Impact factor: 3.411

7.  CD4 T cells in the rheumatoid joint are oligoclonally activated and change during the course of disease.

Authors:  H A Khazaei; C Lunardi; A K So
Journal:  Ann Rheum Dis       Date:  1995-04       Impact factor: 19.103

8.  Analysis of a T-cell receptor V beta segment implicated in susceptibility to rheumatoid arthritis: V beta 2 germline polymorphism does not encode susceptibility.

Authors:  K Pile; P Wordsworth; F Lioté; T Bardin; J Bell; F Cornélis
Journal:  Ann Rheum Dis       Date:  1993-12       Impact factor: 19.103

9.  The human T cell receptor V beta repertoire of normal peripheral blood lymphocytes before and after mitogen stimulation.

Authors:  F S Wong; M L Hibberd; L Wen; B A Millward; A G Demaine
Journal:  Clin Exp Immunol       Date:  1993-05       Impact factor: 4.330

10.  T cell receptor (TCR) Vbeta gene usage in bronchoalveolar lavage and peripheral blood T cells from asthmatic and normal subjects.

Authors:  E Hodges; J Dasmahapatra; J L Smith; C T Quin; S Lanham; M T Krishna; S T Holgate; A J Frew
Journal:  Clin Exp Immunol       Date:  1998-06       Impact factor: 4.330
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