Literature DB >> 14662810

Should HIV discordant couples have access to assisted reproductive technologies?

M Spriggs1, T Charles.   

Abstract

In this paper we identify and evaluate arguments for and against offering assisted reproductive technologies (ART), specifically IVF, to HIV discordant couples (male partner HIV positive, female partner HIV negative). The idea of offering ART to HIV discordant couples generates concerns about safety and public health and raises questions such as: what is an acceptable level of risk to offspring and should couples who want this assistance be subject to selection criteria; should they undergo scrutiny about their suitability as parents when those who are able to conceive naturally face no such scrutiny and people with other illnesses are given access to ART? We conclude that offering ART to HIV discordant couples is likely to produce more benefit than harm and violates no ethical principles. Nevertheless, a decision to deny treatment need not constitute unjustified discrimination.

Entities:  

Keywords:  Genetics and Reproduction; Health Care and Public Health

Mesh:

Year:  2003        PMID: 14662810      PMCID: PMC1733816          DOI: 10.1136/jme.29.6.325

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  22 in total

Review 1.  Use of assisted reproductive technology to reduce the risk of transmission of HIV in discordant couples wishing to have their own children where the male partner is seropositive with an undetectable viral load.

Authors:  H W G Baker; A Mijch; S Garland; S Crowe; M Dunne; D Edgar; G Clarke; P Foster; J Blood
Journal:  J Med Ethics       Date:  2003-12       Impact factor: 2.903

2.  Fatherless families: how important is genetic relatedness?

Authors:  Giuliana Fuscaldo
Journal:  Monash Bioeth Rev       Date:  2002-07

3.  The risk of major birth defects after intracytoplasmic sperm injection and in vitro fertilization.

Authors:  Michèle Hansen; Jennifer J Kurinczuk; Carol Bower; Sandra Webb
Journal:  N Engl J Med       Date:  2002-03-07       Impact factor: 91.245

4.  Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys.

Authors:  Ofelia A Olivero; Juan J Fernandez; Brendan B Antiochos; Jessica L Wagner; Marisa E St Claire; Miriam C Poirier
Journal:  J Acquir Immune Defic Syndr       Date:  2002-04-01       Impact factor: 3.731

5.  A comparison of genetic mitochondrial disease and nucleoside analogue toxicity. Does fetal nucleoside toxicity underlie reports of mitochondrial disease in infants born to women treated for HIV infection?

Authors:  R H Haas
Journal:  Ann N Y Acad Sci       Date:  2000-11       Impact factor: 5.691

6.  Access to services at assisted reproductive technology clinics: a survey of policies and practices.

Authors:  J E Stern; C P Cramer; A Garrod; R M Green
Journal:  Am J Obstet Gynecol       Date:  2001-03       Impact factor: 8.661

Review 7.  ART in HIV-infected couples: has the time come for a change of attitude?

Authors:  Y Englert; J P Van Vooren; I Place; C Liesnard; C Laruelle; A Delbaere
Journal:  Hum Reprod       Date:  2001-07       Impact factor: 6.918

Review 8.  Human immunodeficiency virus and assisted reproduction: reconsidering evidence, reframing ethics.

Authors:  A D Lyerly; J Anderson
Journal:  Fertil Steril       Date:  2001-05       Impact factor: 7.329

9.  Semen analysis in human immunodeficiency virus infection.

Authors:  J A Crittenden; D J Handelsman; G J Stewart
Journal:  Fertil Steril       Date:  1992-06       Impact factor: 7.329

10.  Teratogenicity of recently introduced medications in human pregnancy.

Authors:  W Y Lo; J M Friedman
Journal:  Obstet Gynecol       Date:  2002-09       Impact factor: 7.661

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  3 in total

1.  The new Italian law on assisted reproduction technology (Law 40/2004).

Authors:  V Fineschi; M Neri; E Turillazzi
Journal:  J Med Ethics       Date:  2005-09       Impact factor: 2.903

2.  Fertility intentions among HIV positive women aged 18-49 years in Addis Ababa Ethiopia: a cross sectional study.

Authors:  Hussen Mekonnen Asfaw; Fikre Enquselassie Gashe
Journal:  Reprod Health       Date:  2014-05-20       Impact factor: 3.223

3.  Effect of antiretroviral therapy on changes in the fertility intentions of human immunodeficiency virus-positive women in Addis Ababa, Ethiopia: a prospective follow-up study.

Authors:  Hussen Mekonnen; Fikre Enquselassie
Journal:  Epidemiol Health       Date:  2017-07-16
  3 in total

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