Literature DB >> 14660186

Pragmatic language impairment and social deficits in Williams syndrome: a comparison with Down's syndrome and specific language impairment.

Glynis Laws1, Dorothy Bishop.   

Abstract

BACKGROUND: The social communication strength of individuals with Williams syndrome described by some researchers contrasts with the picture of social difficulties painted by others. AIMS: To study the pragmatic aspects of language, social relationships and unusual interests in a group of children and adults with Williams syndrome, and to compare them with a group of children and adults with Down's syndrome, children with specific language impairment, and a group of typically developing children. METHODS & PROCEDURES: Parents or teachers completed the Children's Communication Checklist or a modified version of it with wording appropriate for adults. Study groups consisted of 19 children and young adults with Williams syndrome, 24 with Down's syndrome, 17 children with specific language impairment and 32 typically developing children. OUTCOMES &
RESULTS: Checklist ratings for the group with Williams syndrome indicated significant levels of pragmatic language impairment, and difficulties with social relationships. Together with evidence of unusual or restricted interests, the results suggested deficits across all three domains covered by the checklist.
CONCLUSIONS: Despite earlier reports that emphasize a strong social interest and empathy, this study suggests that individuals with Williams syndrome have pragmatic language impairments, poor social relationships and restricted interests. Far from representing the polar opposite of autism, as suggested by some researchers, Williams syndrome would seem to share many of the characteristics of autistic disorder.

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Year:  2004        PMID: 14660186     DOI: 10.1080/13682820310001615797

Source DB:  PubMed          Journal:  Int J Lang Commun Disord        ISSN: 1368-2822            Impact factor:   3.020


  56 in total

1.  Children with Williams Syndrome: Language, Cognitive, and Behavioral Characteristics and their Implications for Intervention.

Authors:  Carolyn B Mervis; Shelley L Velleman
Journal:  Perspect Lang Learn Educ       Date:  2011-10-01

Review 2.  Cognitive and behavioral characteristics of children with Williams syndrome: implications for intervention approaches.

Authors:  Carolyn B Mervis; Angela E John
Journal:  Am J Med Genet C Semin Med Genet       Date:  2010-05-15       Impact factor: 3.908

3.  Honing in on the social phenotype in Williams syndrome using multiple measures and multiple raters.

Authors:  Bonita P Klein-Tasman; Kirsten T Li-Barber; Erin T Magargee
Journal:  J Autism Dev Disord       Date:  2011-03

4.  An atypical deletion of the Williams-Beuren syndrome interval implicates genes associated with defective visuospatial processing and autism.

Authors:  Lisa Edelmann; Aaron Prosnitz; Sherly Pardo; Jahnavi Bhatt; Ninette Cohen; Tara Lauriat; Leonid Ouchanov; Patricia J González; Elina R Manghi; Pamela Bondy; Marcela Esquivel; Silvia Monge; Marietha F Delgado; Alessandra Splendore; Uta Francke; Barbara K Burton; L Alison McInnes
Journal:  J Med Genet       Date:  2006-09-13       Impact factor: 6.318

5.  Syntactic comprehension and working memory in children with specific language impairment, autism or Down syndrome.

Authors:  Talita Fortunato-Tavares; Claudia R F Andrade; Debora Befi-Lopes; Suelly O Limongi; Fernanda D M Fernandes; Richard G Schwartz
Journal:  Clin Linguist Phon       Date:  2015-04-22       Impact factor: 1.346

6.  MRI assessment of superior temporal gyrus in Williams syndrome.

Authors:  Adriana Sampaio; Nuno Sousa; Montse Férnandez; Cristiana Vasconcelos; Martha E Shenton; Oscar F Gonçalves
Journal:  Cogn Behav Neurol       Date:  2008-09       Impact factor: 1.600

7.  Overlap with the autism spectrum in young children with Williams syndrome.

Authors:  Bonita P Klein-Tasman; Kristin D Phillips; Catherine Lord; Carolyn B Mervis; Frank J Gallo
Journal:  J Dev Behav Pediatr       Date:  2009-08       Impact factor: 2.225

Review 8.  Bridging the gene-behavior divide through neuroimaging deletion syndromes: Velocardiofacial (22q11.2 Deletion) and Williams (7q11.23 Deletion) syndromes.

Authors:  Daniel Paul Eisenberg; Mbemba Jabbi; Karen Faith Berman
Journal:  Neuroimage       Date:  2010-03-03       Impact factor: 6.556

9.  Theory of mind in Williams syndrome assessed using a nonverbal task.

Authors:  Melanie A Porter; Max Coltheart; Robyn Langdon
Journal:  J Autism Dev Disord       Date:  2008-05

10.  Autonomic responses to dynamic displays of facial expressions in adolescents and adults with Williams syndrome.

Authors:  D Plesa Skwerer; L Borum; A Verbalis; C Schofield; N Crawford; L Ciciolla; H Tager-Flusberg
Journal:  Soc Cogn Affect Neurosci       Date:  2008-11-30       Impact factor: 3.436

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