Literature DB >> 14656838

Cost effectiveness and cost utility model of public place defibrillators in improving survival after prehospital cardiopulmonary arrest.

Andrew Walker1, Jane M Sirel, Andrew K Marsden, Stuart M Cobbe, Jill P Pell.   

Abstract

OBJECTIVE: To determine the cost effectiveness and cost utility of locating defibrillators in all major airports, railway stations, and bus stations throughout Scotland.
DESIGN: Economic modelling exercise with data from Heartstart (Scotland). Parameters used in economic model included direct costs derived for increased accident and emergency attendances, increased hospital bed days, purchase and maintenance of defibrillators, and training in their use; life years gained calculated from increased discharges from hospital and mean survival after discharge; utility (quality of life) obtained from published data. Sensitivity analyses tested the robustness of model. Future gains discounted at 1.5% a year and future costs at 6%.
SETTING: Whole of Scotland.
SUBJECTS: Records of all prehospital cardiac arrests due to presumed heart disease that occurred in a major airport, railway, or bus station between May 1991 and March 1998 and were not witnessed by ambulance or medical staff. MAIN OUTCOME MEASURES: Observed survival to hospital admission and observed survival to discharge. Predicted survival calculated by applying observed survival in patients attended by ambulance staff within three minutes to those who waited longer.
RESULTS: The total discounted direct costs were 18 325 pounds sterling a year. The cost per life year gained was 29 625 pounds sterling (49 625 dollars, 43 151 Euros) and the cost per quality adjusted life year (QALY) gained was pound 41 146 (68 924 dollars, 59 932 Euros). More widespread provision of public place defibrillators would increase these figures.
CONCLUSIONS: The cost per QALY calculated for public place defibrillators represents poorer value for money than some alternative strategies for improving survival after prehospital cardiopulmonary arrest, such as the use of other trained first responders. The figure exceeds the commonly discussed cut off levels for funding in the United Kingdom and United States of pound 30 000 and 50 000 dollars per QALY, respectively.

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Mesh:

Year:  2003        PMID: 14656838      PMCID: PMC286317          DOI: 10.1136/bmj.327.7427.1316

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  14 in total

1.  Cost effectiveness of HMG-CoA reductase inhibitor (statin) treatment related to the risk of coronary heart disease and cost of drug treatment.

Authors:  D M Pickin; C J McCabe; L E Ramsay; N Payne; I U Haq; W W Yeo; P R Jackson
Journal:  Heart       Date:  1999-09       Impact factor: 5.994

Review 2.  Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the Utstein Style. A statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council.

Authors:  R O Cummins; D A Chamberlain; N S Abramson; M Allen; P J Baskett; L Becker; L Bossaert; H H Delooz; W F Dick; M S Eisenberg
Journal:  Circulation       Date:  1991-08       Impact factor: 29.690

3.  Cost-effectiveness analysis of potential improvements to emergency medical services for victims of out-of-hospital cardiac arrest.

Authors:  G Nichol; A Laupacis; I G Stiell; K O'Rourke; A Anis; H Bolley; A S Detsky
Journal:  Ann Emerg Med       Date:  1996-06       Impact factor: 5.721

Review 4.  Cardiopulmonary resuscitation: what cost to cheat death?

Authors:  K H Lee; D C Angus; N S Abramson
Journal:  Crit Care Med       Date:  1996-12       Impact factor: 7.598

5.  Public-access defibrillation: where do we place the AEDs?

Authors:  M Gratton; D J Lindholm; J P Campbell
Journal:  Prehosp Emerg Care       Date:  1999 Oct-Dec       Impact factor: 3.077

6.  Effect of reducing ambulance response times on deaths from out of hospital cardiac arrest: cohort study.

Authors:  J P Pell; J M Sirel; A K Marsden; I Ford; S M Cobbe
Journal:  BMJ       Date:  2001-06-09

Review 7.  Public access defibrillation: a shocking idea?

Authors:  M Woollard
Journal:  J Public Health Med       Date:  2001-06

8.  Cost-effectiveness of automated external defibrillators on airlines.

Authors:  P W Groeneveld; J L Kwong; Y Liu; A J Rodriguez; M P Jones; G D Sanders; A M Garber
Journal:  JAMA       Date:  2001-09-26       Impact factor: 56.272

9.  Cost-effectiveness of routine coronary angiography after acute myocardial infarction.

Authors:  K M Kuntz; J Tsevat; L Goldman; M C Weinstein
Journal:  Circulation       Date:  1996-09-01       Impact factor: 29.690

10.  Potential impact of public access defibrillators on survival after out of hospital cardiopulmonary arrest: retrospective cohort study.

Authors:  Jill P Pell; Jane M Sirel; Andrew K Marsden; Ian Ford; Nicola L Walker; Stuart M Cobbe
Journal:  BMJ       Date:  2002-09-07
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  8 in total

1.  Need for differential discounting of costs and health effects in cost effectiveness analyses.

Authors:  Werner B F Brouwer; Louis W Niessen; Maarten J Postma; Frans F H Rutten
Journal:  BMJ       Date:  2005-08-20

Review 2.  [Public access defibrillation. Limited use by trained first responders and laymen].

Authors:  S Maisch; P Friederich; A E Goetz
Journal:  Anaesthesist       Date:  2006-12       Impact factor: 1.041

3.  Favourable cost-benefit in an early defibrillation programme using dual dispatch of ambulance and fire services in out-of-hospital cardiac arrest.

Authors:  Björn Sund; Leif Svensson; Mårten Rosenqvist; Jacob Hollenberg
Journal:  Eur J Health Econ       Date:  2011-07-08

4.  Use of automated external defibrillators in cardiac arrest: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2005-12-01

Review 5.  Ventricular fibrillation and defibrillation.

Authors:  P Jones; N Lodé
Journal:  Arch Dis Child       Date:  2007-10       Impact factor: 3.791

6.  Out of hospital cardiac arrest outside home in Sweden, change in characteristics, outcome and availability for public access defibrillation.

Authors:  Mattias Ringh; Johan Herlitz; Jacob Hollenberg; Mårten Rosenqvist; Leif Svensson
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2009-04-17       Impact factor: 2.953

7.  Hospital costs of out-of-hospital cardiac arrest patients treated in intensive care; a single centre evaluation using the national tariff-based system.

Authors:  J Petrie; S Easton; V Naik; C Lockie; S J Brett; R Stümpfle
Journal:  BMJ Open       Date:  2015-04-02       Impact factor: 2.692

8.  Support and Assessment for Fall Emergency Referrals (SAFER 1) trial protocol. Computerised on-scene decision support for emergency ambulance staff to assess and plan care for older people who have fallen: evaluation of costs and benefits using a pragmatic cluster randomised trial.

Authors:  Helen Snooks; Wai-Yee Cheung; Jacqueline Close; Jeremy Dale; Sarah Gaze; Ioan Humphreys; Ronan Lyons; Suzanne Mason; Yasmin Merali; Julie Peconi; Ceri Phillips; Judith Phillips; Stephen Roberts; Ian Russell; Antonio Sánchez; Mushtaq Wani; Bridget Wells; Richard Whitfield
Journal:  BMC Emerg Med       Date:  2010-01-26
  8 in total

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