Literature DB >> 14656790

Retrieving organs from non-heart-beating organ donors: a review of medical and ethical issues.

Christopher James Doig1, Graeme Rocker.   

Abstract

PURPOSE: The increasing gap between numbers of individuals awaiting organ replacement surgery and the supply of organs available for transplant underpins attempts to increase the number of organs available. One practice, used in other countries, is the recovery of organs from non-heart-beating organ donors (NHBD). The purpose of this review is to discuss ethical issues surrounding the use of organs from these donors. SOURCE: Narrative review from selected Medline references, and other published reports. PRINCIPAL
FINDINGS: NHBD protocols have been established in many countries including the United States. Despite numerous publications, and extensive debate in the literature, significant ethical issues remain unresolved in the retrieval of organs from donors that have died from cessation of cardiac activity. The ethical concerns primarily arise in the determination of death, the tension between the time constraints on recovering organs viable for transplantation, and procedures to enhance organ viability. Despite a concerted effort in the United States, less than half of the organ procurement organizations have NHBD protocols.
CONCLUSION: Canadian centres can learn from the difficulties encountered in other centres that have developed NHBD protocols. A moratorium on Canadian NHBD protocols should be considered until a National consensus reflecting Canadian values has been undertaken.

Keywords:  Death and Euthanasia; Health Care and Public Health

Mesh:

Year:  2003        PMID: 14656790     DOI: 10.1007/BF03018376

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN: 0832-610X            Impact factor:   5.063


  9 in total

Review 1.  Kidney donation after cardiac death.

Authors:  Jacob A Akoh
Journal:  World J Nephrol       Date:  2012-06-06

Review 2.  End of life issues in the intensive care units.

Authors:  Rashmi Datta; R Chaturvedi; A Rudra; C N Jaideep
Journal:  Med J Armed Forces India       Date:  2012-10-23

Review 3.  Nonheart-beating donation in the neurologically devastated patient.

Authors:  Edward M Manno
Journal:  Neurocrit Care       Date:  2005       Impact factor: 3.210

4.  In defense of the reverence of all life: Heideggerean dissolution of the ethical challenges of organ donation after circulatory determination of death.

Authors:  D J Isch
Journal:  Med Health Care Philos       Date:  2007-05-02

5.  Donation after cardiac death: a survey of university student opinions on death and donation.

Authors:  Ari R Joffe; Roisin Byrne; Natalie R Anton; Allan R deCaen
Journal:  Intensive Care Med       Date:  2008-08-01       Impact factor: 17.440

6.  The ethics of organ donation after cardiocirculatory death: Do the guidelines of the Canadian Council for Donation and Transplantation measure up?

Authors:  Alister Browne
Journal:  Open Med       Date:  2010-06-29

7.  Kidney retrieval after sudden out of hospital refractory cardiac arrest: a cohort of uncontrolled non heart beating donors.

Authors:  Fabienne Fieux; Marie-Reine Losser; Eric Bourgeois; Francine Bonnet; Olivier Marie; François Gaudez; Imad Abboud; Jean-Luc Donay; France Roussin; François Mourey; Frédéric Adnet; Laurent Jacob
Journal:  Crit Care       Date:  2009-08-28       Impact factor: 9.097

8.  Early reperfusion hemodynamics predict recovery in rat hearts: a potential approach towards evaluating cardiac grafts from non-heart-beating donors.

Authors:  Monika Dornbierer; Mathieu Stadelmann; Joevin Sourdon; Brigitta Gahl; Stéphane Cook; Thierry P Carrel; Hendrik T Tevaearai; Sarah L Longnus
Journal:  PLoS One       Date:  2012-08-21       Impact factor: 3.240

9.  Truthfulness in transplantation: non-heart-beating organ donation.

Authors:  Michael Potts
Journal:  Philos Ethics Humanit Med       Date:  2007-08-24       Impact factor: 2.464

  9 in total

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