Literature DB >> 14654243

Molecular cloning of PP2Ceta, a novel member of the protein phosphatase 2C family.

Ken-ichiro Komaki1, Koji Katsura, Motoko Ohnishi, Ming Guang Li, Masato Sasaki, Makoto Watanabe, Takayasu Kobayashi, Shinri Tamura.   

Abstract

We have cloned a novel member of the mouse protein phosphatase 2C family, PP2Ceta. Sequence analysis suggests that PP2Ceta, PP2Czeta and NERPP-2C constitute a unique subgroup of the PP2C family. PP2Ceta had extremely low activity against alpha-casein compared with PP2Calpha and was localized mainly in cell nuclei, suggesting that PP2Ceta dephosphorylates a unique nuclear protein(s) in the cells.

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Year:  2003        PMID: 14654243     DOI: 10.1016/j.bbaexp.2003.09.004

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  7 in total

1.  Evolution of the metazoan protein phosphatase 2C superfamily.

Authors:  Adi Stern; Eyal Privman; Michal Rasis; Sara Lavi; Tal Pupko
Journal:  J Mol Evol       Date:  2006-12-06       Impact factor: 2.395

2.  Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells.

Authors:  Luke A Gilbert; Sandeep Ravindran; Jay M Turetzky; John C Boothroyd; Peter J Bradley
Journal:  Eukaryot Cell       Date:  2006-11-03

3.  Identification of a novel PP2C-type mitochondrial phosphatase.

Authors:  Mandar Joshi; Nam Ho Jeoung; Kirill M Popov; Robert A Harris
Journal:  Biochem Biophys Res Commun       Date:  2007-02-28       Impact factor: 3.575

4.  Structural and biochemical characterization of human mitochondrial branched-chain α-ketoacid dehydrogenase phosphatase.

Authors:  R Max Wynn; Jun Li; Chad A Brautigam; Jacinta L Chuang; David T Chuang
Journal:  J Biol Chem       Date:  2012-01-30       Impact factor: 5.157

5.  Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon.

Authors:  Jun-ichi Saito; Shinnosuke Toriumi; Kenjiro Awano; Hidenori Ichijo; Keiichi Sasaki; Takayasu Kobayashi; Shinri Tamura
Journal:  Biochem J       Date:  2007-08-01       Impact factor: 3.857

6.  Nuclear phosphatase PPM1G in cellular survival and neural development.

Authors:  William H Foster; Adam Langenbacher; Chen Gao; Jaunian Chen; Yibin Wang
Journal:  Dev Dyn       Date:  2013-07-26       Impact factor: 2.842

7.  Novel progressive acrodysostosis-like skeletal dysplasia, cerebellar atrophy, and ichthyosis.

Authors:  Harvy M Velasco; Ehsan Ullah; Angela M Martin; Robert B Hufnagel; Carlos E Prada
Journal:  Am J Med Genet A       Date:  2020-08-11       Impact factor: 2.578

  7 in total

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