Literature DB >> 14654223

Roc, a Ras/GTPase domain in complex proteins.

Leonard Bosgraaf1, Peter J M Van Haastert.   

Abstract

We identified a novel group of the Ras/GTPase superfamily, termed Roc, that is present as domain in complex proteins together with other domains, including leucine-rich repeats (LRRs), ankyrin repeats, WD40 repeats, kinase domains, RasGEF and RhoGAP domains. Roc is always succeeded by a novel 300-400-amino-acid-long domain, termed COR. Proteins with Roc/COR are present in prokaryotes, Dictyostelium, plants and metazoa.

Mesh：

Substances：

Year:  2003        PMID： 14654223     DOI： 10.1016/j.bbamcr.2003.08.008

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  116 in total

1.  Multiple regulatory mechanisms for the Dictyostelium Roco protein GbpC.

Authors:  Arjan Kortholt; Wouter N van Egmond; Katarzyna Plak; Leonard Bosgraaf; Ineke Keizer-Gunnink; Peter J M van Haastert
Journal:  J Biol Chem       Date:  2011-11-26       Impact factor: 5.157

2.  Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant.

Authors:  Veronique Daniëls; Renée Vancraenenbroeck; Bernard M H Law; Elisa Greggio; Evy Lobbestael; Fangye Gao; Marc De Maeyer; Mark R Cookson; Kirsten Harvey; Veerle Baekelandt; Jean-Marc Taymans
Journal:  J Neurochem       Date:  2011-01       Impact factor: 5.372

3.  Leucine-rich repeat kinase 2: a new player with a familiar theme for Parkinson's disease pathogenesis.

Authors:  Chenjian Li; M Flint Beal
Journal:  Proc Natl Acad Sci U S A       Date:  2005-11-07       Impact factor: 11.205

Review 4.  The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2.

Authors:  Vincenzo Bonifati
Journal:  Curr Neurol Neurosci Rep       Date:  2006-09       Impact factor: 5.081

5.  A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics.

Authors:  Andrea Meixner; Karsten Boldt; Marleen Van Troys; Manor Askenazi; Christian J Gloeckner; Matthias Bauer; Jarrod A Marto; Christophe Ampe; Norbert Kinkl; Marius Ueffing
Journal:  Mol Cell Proteomics       Date:  2010-09-27       Impact factor: 5.911

6.  The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules.

Authors:  Payal N Gandhi; Xinglong Wang; Xiongwei Zhu; Shu G Chen; Amy L Wilson-Delfosse
Journal:  J Neurosci Res       Date:  2008-06       Impact factor: 4.164

7.  Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury.

Authors:  Ravindra Boddu; Travis D Hull; Subhashini Bolisetty; Xianzhen Hu; Mark S Moehle; João Paulo Lima Daher; Ahmed Ibrahim Kamal; Reny Joseph; James F George; Anupam Agarwal; Lisa M Curtis; Andrew B West
Journal:  Hum Mol Genet       Date:  2015-04-22       Impact factor: 6.150

Review 8.  The LRRK2 G2019S mutation as the cause of Parkinson's disease in Ashkenazi Jews.

Authors:  Avner Thaler; Elissa Ash; Ziv Gan-Or; Avi Orr-Urtreger; Nir Giladi
Journal:  J Neural Transm (Vienna)       Date:  2009-11       Impact factor: 3.575

9.  Identification of biallelic LRRK1 mutations in osteosclerotic metaphyseal dysplasia and evidence for locus heterogeneity.

Authors:  Aritoshi Iida; Weirong Xing; Martine K F Docx; Tomoki Nakashima; Zheng Wang; Mamori Kimizuka; Wim Van Hul; Dietz Rating; Jürgen Spranger; Hirohumi Ohashi; Noriko Miyake; Naomichi Matsumoto; Subburaman Mohan; Gen Nishimura; Geert Mortier; Shiro Ikegawa
Journal:  J Med Genet       Date:  2016-04-07       Impact factor: 6.318

10.  Characterization of the Roco protein family in Dictyostelium discoideum.

Authors:  Wouter N van Egmond; Peter J M van Haastert
Journal:  Eukaryot Cell       Date:  2010-03-26
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.