Literature DB >> 16928343

The pleomorphic pathology of inherited Parkinson's disease: lessons from LRRK2.

Vincenzo Bonifati1.   

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Year:  2006        PMID： 16928343     DOI： 10.1007/s11910-996-0013-z

Source DB:  PubMed          Journal:  Curr Neurol Neurosci Rep        ISSN： 1528-4042            Impact factor:   5.081


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  20 in total

1.  Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*.

Authors:  Daniela Berg; Katherine J Schweitzer; Petra Leitner; Alexander Zimprich; Peter Lichtner; Petra Belcredi; Theresa Brüssel; Claudia Schulte; Sylvia Maass; Thomas Nägele; Zbigniew K Wszolek; Thomas Gasser
Journal:  Brain       Date:  2005-12       Impact factor: 13.501

2.  LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.

Authors:  Laurie J Ozelius; Geetha Senthil; Rachel Saunders-Pullman; Erin Ohmann; Amanda Deligtisch; Michele Tagliati; Ann L Hunt; Christine Klein; Brian Henick; Susan M Hailpern; Richard B Lipton; Jeannie Soto-Valencia; Neil Risch; Susan B Bressman
Journal:  N Engl J Med       Date:  2006-01-26       Impact factor: 91.245

3.  Lrrk2 and Lewy body disease.

Authors:  Owen A Ross; Mathias Toft; Andrew J Whittle; Joseph L Johnson; Spiridon Papapetropoulos; Deborah C Mash; Irene Litvan; Mark F Gordon; Zbigniew K Wszolek; Matthew J Farrer; Dennis W Dickson
Journal:  Ann Neurol       Date:  2006-02       Impact factor: 10.422

4.  Biochemical and pathological characterization of Lrrk2.

Authors:  Benoit I Giasson; Jason P Covy; Nancy M Bonini; Howard I Hurtig; Matthew J Farrer; John Q Trojanowski; Vivianna M Van Deerlin
Journal:  Ann Neurol       Date:  2006-02       Impact factor: 10.422

5.  Lrrk2 pathogenic substitutions in Parkinson's disease.

Authors:  Ignacio F Mata; Jennifer M Kachergus; Julie P Taylor; Sarah Lincoln; Jan Aasly; Timothy Lynch; Mary M Hulihan; Stephanie A Cobb; Ruey-Meei Wu; Chin-Song Lu; Carlos Lahoz; Zbigniew K Wszolek; Matthew J Farrer
Journal:  Neurogenetics       Date:  2005-09-17       Impact factor: 2.660

Review 6.  Molecular pathophysiology of Parkinson's disease.

Authors:  Darren J Moore; Andrew B West; Valina L Dawson; Ted M Dawson
Journal:  Annu Rev Neurosci       Date:  2005       Impact factor: 12.449

7.  A common LRRK2 mutation in idiopathic Parkinson's disease.

Authors:  William P Gilks; Patrick M Abou-Sleiman; Sonia Gandhi; Shushant Jain; Andrew Singleton; Andrew J Lees; Karen Shaw; Kailash P Bhatia; Vincenzo Bonifati; Niall P Quinn; John Lynch; Daniel G Healy; Janice L Holton; Tamas Revesz; Nicholas W Wood
Journal:  Lancet       Date:  2005 Jan 29-Feb 4       Impact factor: 79.321

8.  Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.

Authors:  Alessio Di Fonzo; Cristina Tassorelli; Michele De Mari; Hsin F Chien; Joaquim Ferreira; Christan F Rohé; Giulio Riboldazzi; Angelo Antonini; Gianni Albani; Alessandro Mauro; Roberto Marconi; Giovanni Abbruzzese; Leonardo Lopiano; Emiliana Fincati; Marco Guidi; Paolo Marini; Fabrizio Stocchi; Marco Onofrj; Vincenzo Toni; Michele Tinazzi; Giovanni Fabbrini; Paolo Lamberti; Nicola Vanacore; Giuseppe Meco; Petra Leitner; Ryan J Uitti; Zbigniew K Wszolek; Thomas Gasser; Erik J Simons; Guido J Breedveld; Stefano Goldwurm; Gianni Pezzoli; Cristina Sampaio; Egberto Barbosa; Emilia Martignoni; Ben A Oostra; Vincenzo Bonifati
Journal:  Eur J Hum Genet       Date:  2006-03       Impact factor: 4.246

9.  Kinase activity is required for the toxic effects of mutant LRRK2/dardarin.

Authors:  Elisa Greggio; Shushant Jain; Ann Kingsbury; Rina Bandopadhyay; Patrick Lewis; Alice Kaganovich; Marcel P van der Brug; Alexandra Beilina; Jeff Blackinton; Kelly Jean Thomas; Rili Ahmad; David W Miller; Sashi Kesavapany; Andrew Singleton; Andrew Lees; Robert J Harvey; Kirsten Harvey; Mark R Cookson
Journal:  Neurobiol Dis       Date:  2006-06-05       Impact factor: 5.996

10.  The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor.

Authors:  S Goldwurm; A Di Fonzo; E J Simons; C F Rohé; M Zini; M Canesi; S Tesei; A Zecchinelli; A Antonini; C Mariani; N Meucci; G Sacilotto; F Sironi; G Salani; J Ferreira; H F Chien; E Fabrizio; N Vanacore; A Dalla Libera; F Stocchi; C Diroma; P Lamberti; C Sampaio; G Meco; E Barbosa; A M Bertoli-Avella; G J Breedveld; B A Oostra; G Pezzoli; V Bonifati
Journal:  J Med Genet       Date:  2005-11       Impact factor: 6.318
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  5 in total

1.  Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.

Authors:  Guoxiang Liu; Carmelo Sgobio; Xinglong Gu; Lixin Sun; Xian Lin; Jia Yu; Loukia Parisiadou; Chengsong Xie; Namratha Sastry; Jinhui Ding; Kelly M Lohr; Gary W Miller; Yolanda Mateo; David M Lovinger; Huaibin Cai
Journal:  Hum Mol Genet       Date:  2015-06-29       Impact factor: 6.150

Review 2.  LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease.

Authors:  Vincenzo Bonifati
Journal:  Neurochem Res       Date:  2007-04-18       Impact factor: 3.996

3.  Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export.

Authors:  Hyun Jin Cho; Jia Yu; Chengsong Xie; Parvathi Rudrabhatla; Xi Chen; Junbing Wu; Loukia Parisiadou; Guoxiang Liu; Lixin Sun; Bo Ma; Jinhui Ding; Zhihua Liu; Huaibin Cai
Journal:  EMBO J       Date:  2014-09-08       Impact factor: 11.598

4.  Familial knockin mutation of LRRK2 causes lysosomal dysfunction and accumulation of endogenous insoluble α-synuclein in neurons.

Authors:  Jason Schapansky; Saurabh Khasnavis; Mark P DeAndrade; Jonathan D Nardozzi; Samuel R Falkson; Justin D Boyd; John B Sanderson; Tim Bartels; Heather L Melrose; Matthew J LaVoie
Journal:  Neurobiol Dis       Date:  2017-12-12       Impact factor: 5.996

5.  LRRK2 affects vesicle trafficking, neurotransmitter extracellular level and membrane receptor localization.

Authors:  Rossana Migheli; Maria Grazia Del Giudice; Ylenia Spissu; Giovanna Sanna; Yulan Xiong; Ted M Dawson; Valina L Dawson; Manuela Galioto; Gaia Rocchitta; Alice Biosa; Pier Andrea Serra; Maria Teresa Carri; Claudia Crosio; Ciro Iaccarino
Journal:  PLoS One       Date:  2013-10-22       Impact factor: 3.240
  5 in total

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