Literature DB >> 14653697

Enantioselective syntheses of ring-C precursors of vitamin B12. Substrate control. A novel Si-assisted elimination of vinyl bromides.

Peter A Jacobi1, Carlos Tassa.   

Abstract

Homochiral ring-C precursors 34 of Vitamin B(12) have been prepared by Ireland-Claisen rearrangement of allyl esters 32, followed by a novel Si-assisted elimination of HBr. [reaction: see text]

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Year:  2003        PMID: 14653697     DOI: 10.1021/ol036061u

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  Toward the synthesis of cobyric acid. Enantioselective syntheses of completely differentiated ring D synthons.

Authors:  Hui Wang; Carlos Tassa; Peter A Jacobi
Journal:  Org Lett       Date:  2008-06-07       Impact factor: 6.005

2.  Studies in chlorin chemistry. II. A versatile synthesis of dihydrodipyrrins.

Authors:  William G O'Neal; William P Roberts; Indranath Ghosh; Peter A Jacobi
Journal:  J Org Chem       Date:  2005-09-02       Impact factor: 4.354

  2 in total

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