| Literature DB >> 14643331 |
Keith G Rosauer1, Anthony K Ogawa, Chris A Willoughby, Kenneth P Ellsworth, Wayne M Geissler, Robert W Myers, Qiaolin Deng, Kevin T Chapman, Georgianna Harris, David E Moller.
Abstract
The preparation of a series of substituted indoles coupled to six- and seven-membered cyclic lactams is described and their role as human glycogen phosphorylase a inhibitors discussed. The SAR of the indole moiety and lactam ring are presented.Entities:
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Year: 2003 PMID： 14643331 DOI： 10.1016/j.bmcl.2003.09.022
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823