Literature DB >> 14641613

Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.

Andrew J MacGinnitie1, Loren D Walensky, Stuart E Turvey, Jordan S Orange, Francisco A Bonilla, Lewis B Silverman, Hans Oettgen.   

Abstract

We report the management of a 15-year-old boy with an anaphylactic or anaphylactoid response to his first dose of methotrexate during induction therapy for acute lymphoblastic leukemia (ALL). Because weekly methotrexate therapy is an important component of continuation chemotherapy for pediatric ALL, a stepwise graded challenge was employed to achieve drug tolerance.

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Year:  2003        PMID: 14641613     DOI: 10.1034/j.1399-3038.2003.00073.x

Source DB:  PubMed          Journal:  Pediatr Allergy Immunol        ISSN: 0905-6157            Impact factor:   6.377


  3 in total

1.  Hypersensitivity reaction to high-dose methotrexate and successful rechallenge in a pediatric patient with osteosarcoma.

Authors:  Jeffrey R Scott; Deborah A Ward; Kristine R Crews; John C Panetta; Fariba Navid
Journal:  Pediatr Blood Cancer       Date:  2013-08-19       Impact factor: 3.167

2.  Methotrexate hypersensitivity reactions in pediatrics: Evaluation and management.

Authors:  Meredith A Dilley; Joyce P Lee; Ana Dioun Broyles
Journal:  Pediatr Blood Cancer       Date:  2016-10-27       Impact factor: 3.167

3.  Successful rapid drug desensitization to methotrexate in a patient with primary central nervous system lymphoma.

Authors:  Kyung Mee Song; Junghwan Lee; Ji Hyun Park; So-Young Park; Tae-Bum Kim; Cheolwon Suh
Journal:  Blood Res       Date:  2018-03-27
  3 in total

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