Literature DB >> 14641542

Promoter polymorphisms of the CD14 gene are not associated with bronchial asthma in Caucasian children.

A Heinzmann1, H Dietrich, S-P Jerkic, T Kurz, K A Deichmann.   

Abstract

Several studies have investigated the association of a promoter polymorphism in CD14 with atopic phenotypes. We screened this and another polymorphism in 182 asthmatic children and found no association with asthma. Furthermore, there was substantial linkage disequilibrium of the polymorphisms. Thus CD14 does not play a major role in the development of asthma in our population of Caucasian children.

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Year:  2003        PMID: 14641542     DOI: 10.1046/j.1365-2370.2003.00414.x

Source DB:  PubMed          Journal:  Eur J Immunogenet        ISSN: 0960-7420


  14 in total

1.  Suggestive evidence of association of C-159T functional polymorphism of the CD14 gene with atopic asthma in northern and northwestern Indian populations.

Authors:  Mamta Sharma; Jyotsna Batra; U Mabalirajan; Sangeeta Goswami; Dipyaman Ganguly; Brajen Lahkar; N K Bhatia; Amrendra Kumar; Balaram Ghosh
Journal:  Immunogenetics       Date:  2004-09-18       Impact factor: 2.846

2.  The -159C/T polymorphism in the CD14 gene and the risk of asthma: a meta-analysis.

Authors:  Yonggang Zhang; Can Tian; Jie Zhang; Xiaobo Li; Hua Wan; Chao He; Liang Guo; Quocuo Meilang; Chunhong Peng; Lina Duo; Jin Huang; Hong Fan
Journal:  Immunogenetics       Date:  2010-11-16       Impact factor: 2.846

3.  No Association Between -159C/T Polymorphism of the CD14 Gene and Asthma Risk: a Meta-Analysis of 36 Case-Control Studies.

Authors:  Rui Zhang; Rui Deng; He Li; Hong Chen
Journal:  Inflammation       Date:  2016-02       Impact factor: 4.092

4.  Role of infections in the induction and development of asthma: genetic and inflammatory drivers.

Authors:  Qun Wu; Hong Wei Chu
Journal:  Expert Rev Clin Immunol       Date:  2009-01-01       Impact factor: 4.473

Review 5.  Genetic determinants and ethnic disparities in sepsis-associated acute lung injury.

Authors:  Kathleen C Barnes
Journal:  Proc Am Thorac Soc       Date:  2005

6.  The CD14 C-159T polymorphism is not associated with asthma or asthma severity in an Australian adult population.

Authors:  M-A Kedda; F Lose; D Duffy; E Bell; P J Thompson; J Upham
Journal:  Thorax       Date:  2005-03       Impact factor: 9.139

Review 7.  Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta-analysis.

Authors:  Linlu Zhao; Michael B Bracken
Journal:  BMC Med Genet       Date:  2011-07-11       Impact factor: 2.103

8.  Genetic polymorphisms and associated susceptibility to asthma.

Authors:  Michael E March; Patrick Ma Sleiman; Hakon Hakonarson
Journal:  Int J Gen Med       Date:  2013-04-17

9.  A systematic review of CD14 and toll-like receptors in relation to asthma in Caucasian children.

Authors:  Ester Mm Klaassen; Brenda Ejt Thönissen; Guillaume van Eys; Edward Dompeling; Quirijn Jöbsis
Journal:  Allergy Asthma Clin Immunol       Date:  2013-03-15       Impact factor: 3.406

10.  The effect of CD14 and TLR4 gene polymorphisms on asthma phenotypes in adult Turkish asthma patients: a genetic study.

Authors:  Füsun Sahin; Pınar Yıldız; Ayşegül Kuskucu; Mert Ahmet Kuskucu; Nilgün Karaca; Kenan Midilli
Journal:  BMC Pulm Med       Date:  2014-02-13       Impact factor: 3.317

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