Literature DB >> 14640517

New cytotoxic sesterterpenoids and norsesterterpenoids from two sponges of the genus Sarcotragus.

Yonghong Liu1, Tayyab A Mansoor, Jongki Hong, Chong-O Lee, Chung Ja Sim, Kwang Sik Im, Nam Deuk Kim, Jee H Jung.   

Abstract

New norsesterterpenoids (3 and 4), a sesterterpenoid (6), pyrroloterpenoids (7-10), and a stereoisomer of kurospongin (5) were isolated, along with known furanosesterterpenes (11-15), from two marine sponges of the genus Sarcotragus. The gross structures were established on the basis of NMR and MS analysis. The stereochemistry was defined by combined use of NMR and CD spectroscopy. The compounds were evaluated for cytotoxicity against five human tumor cell lines and were found to exhibit marginal to moderate activity.

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Year:  2003        PMID： 14640517     DOI： 10.1021/np030268e

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Rhabdastrellic acid-A induced autophagy-associated cell death through blocking Akt pathway in human cancer cells.

Authors:  Dan-Dan Li; Jing-Feng Guo; Jia-Jia Huang; Lin-Lin Wang; Rong Deng; Jian-Nan Liu; Gong-Kan Feng; Ding-Jun Xiao; Song-Zhi Deng; Xiao-Shi Zhang; Xiao-Feng Zhu
Journal:  PLoS One       Date:  2010-08-17       Impact factor: 3.240

2.  Glycerolipids from a Sarcotragus species sponge.

Authors:  Yonghong Liu; Jee H Jung; Hong Ji; Si Zhang
Journal:  Molecules       Date:  2006-09-28       Impact factor: 4.411

3.  Plakortinic Acids A and B: Cytotoxic Cycloperoxides with a Bicyclo[4.2.0]octene Unit from Sponges of the Genera Plakortis and Xestospongia.

Authors:  Carlos Jiménez-Romero; Abimael D Rodríguez; Sangkil Nam
Journal:  Org Lett       Date:  2017-03-08       Impact factor: 6.072

Review 4.  Targeting cancer with sesterterpenoids: the new potential antitumor drugs.

Authors:  Caiguo Zhang; Yan Liu
Journal:  J Nat Med       Date:  2015-04-19       Impact factor: 2.343

5.  Total synthesis of the proposed structure of astakolactin.

Authors:  Takayuki Tonoi; Keisuke Mameda; Moe Fujishiro; Yutaka Yoshinaga; Isamu Shiina
Journal:  Beilstein J Org Chem       Date:  2014-10-17       Impact factor: 2.883

6.  In Vitro Growth Inhibitory Activities of Natural Products from Irciniid Sponges against Cancer Cells: A Comparative Study.

Authors:  Yosr BenRedjem Romdhane; Monia Elbour; Marianna Carbone; Maria Letizia Ciavatta; Margherita Gavagnin; Véronique Mathieu; Florence Lefranc; Leila Ktari; Karim Ben Mustapha; Abdellatif Boudabous; Robert Kiss; Ernesto Mollo
Journal:  Biomed Res Int       Date:  2016-08-11       Impact factor: 3.411

7.  Furanoterpene Diversity and Variability in the Marine Sponge Spongia officinalis, from Untargeted LC-MS/MS Metabolomic Profiling to Furanolactam Derivatives.

Authors:  Cléa Bauvais; Natacha Bonneau; Alain Blond; Thierry Pérez; Marie-Lise Bourguet-Kondracki; Séverine Zirah
Journal:  Metabolites       Date:  2017-06-13

8.  In Search of Alternative Antibiotic Drugs: Quorum-Quenching Activity in Sponges and their Bacterial Isolates.

Authors:  Kumar Saurav; Rinat Bar-Shalom; Markus Haber; Ilia Burgsdorf; Giorgia Oliviero; Valeria Costantino; David Morgenstern; Laura Steindler
Journal:  Front Microbiol       Date:  2016-04-05       Impact factor: 5.640
  8 in total

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