| Literature DB >> 14640379 |
E Torrents1, I Boiso, P N Barri, A Veiga.
Abstract
Nowadays, high-dose chemotherapy and radiotherapy treatments for cancer are more effective but can severely affect the ovarian follicular store, compromising the fertility of surviving young patients. A promising alternative to prevent fertility loss in these patients is the cryopreservation and transplantation of ovarian tissue. Slices of animal and human ovarian tissue have been shown to survive the cryopreservation process. After transplantation, follicular development and restoration of hormone secretion have been observed in animal and human studies. This review addresses recent developments on ovarian tissue transplantation in animals and humans. We also illustrate the indications and technical difficulties of the procedure and the ethical issues that should be considered.Entities:
Mesh：
Year: 2003 PMID： 14640379 DOI： 10.1093/humupd/dmg036
Source DB: PubMed Journal: Hum Reprod Update ISSN： 1355-4786 Impact factor: 15.610