Literature DB >> 14639190

[Taurine: a particular aminoacid with multiple functions].

M Bidri, P Choay.   

Abstract

Taurine has multiple biological and metabolic functions: this particular B-amino acid is an antioxidant, it conjugates biliary acids, detoxifies some xenobiotics and modulates intracellular calcium levels. Moreover, taurine plays an important part in osmoregulation, neuromodulation and stabilization of the membranes. Taurine is looked upon as an "essential amino acid" in some particular situations associating inadequate intake or synthesis and major loss of biliary salts. Clinically, taurine has been used with varying degrees of success in the treatment of several pathologies (cardiovascular diseases, cystic fibrosis, alcoholism, retinal degeneration, hepatic disorders). Being found in the secretions of the mammalian reproductive tract, it preserves the motility of the spermatozoa, supports their capacitation, improves the chances of success of fertilization and the early embryonic development. This is why it can be found in some culture media for in vitro fertilization.

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Year:  2003        PMID: 14639190

Source DB:  PubMed          Journal:  Ann Pharm Fr        ISSN: 0003-4509


  4 in total

1.  Taurine Attenuates Hepatic Inflammation in Chronic Alcohol-Fed Rats Through Inhibition of TLR4/MyD88 Signaling.

Authors:  Chao-Jen Lin; Chun-Ching Chiu; Yi-Chen Chen; Mu-Lin Chen; Tsai-Ching Hsu; Bor-Show Tzang
Journal:  J Med Food       Date:  2015-06-19       Impact factor: 2.786

2.  Taurine trial in succinic semialdehyde dehydrogenase deficiency and elevated CNS GABA.

Authors:  Phillip L Pearl; John Schreiber; William H Theodore; Robert McCarter; Emily S Barrios; Joe Yu; Edythe Wiggs; Jianping He; K Michael Gibson
Journal:  Neurology       Date:  2014-02-12       Impact factor: 9.910

3.  Biomarkers in a Taurine Trial for Succinic Semialdehyde Dehydrogenase Deficiency.

Authors:  John M Schreiber; Phillip L Pearl; Irene Dustin; Edythe Wiggs; Emily Barrios; Eric M Wassermann; K Michael Gibson; William H Theodore
Journal:  JIMD Rep       Date:  2016-06-24

4.  Effects of taurine on resting-state fMRI activity in spontaneously hypertensive rats.

Authors:  Vincent Chin-Hung Chen; Tsai-Ching Hsu; Li-Jeng Chen; Hong-Chun Chou; Jun-Cheng Weng; Bor-Show Tzang
Journal:  PLoS One       Date:  2017-07-10       Impact factor: 3.240

  4 in total

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