OBJECTIVES: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging. METHODS: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls. RESULTS: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated. CONCLUSIONS: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.
OBJECTIVES: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging. METHODS: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls. RESULTS: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated. CONCLUSIONS: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.
Authors: M Preuss; K-T Hoffmann; M Reiss-Zimmermann; W Hirsch; A Merkenschlager; J Meixensberger; M Dengl Journal: Childs Nerv Syst Date: 2013-07-07 Impact factor: 1.475
Authors: Marcio Luciano de Souza Bezerra; Ana Carolina Andorinho de Freitas Ferreira; Ricardo de Oliveira-Souza Journal: Front Neurol Date: 2018-01-16 Impact factor: 4.003