| Literature DB >> 14633246 |
T Kanbayashi, Y Inoue, K Kawanishi, H Takasaki, R Aizawa, K Takahashi, Y Ogawa, M Abe, Y Hishikawa, T Shimizu.
Abstract
The majority of patients with narcolepsy-cataplexy were reported to have very low cerebrospinal fluid (CSF) hypocretin-1 (orexin-A) levels. The hypocretin-1 levels of secondary excessive daytime sleepiness (EDS) disorders are not known. In this study, we found that CSF hypocretin levels in the patients with obstructive sleep apnea syndrome were within the control range. The low hypocretin levels seem to reflect only the presence of cataplexy and DR2 positive in narcoleptics but not EDS itself.Entities:
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Year: 2003 PMID： 14633246 DOI： 10.1046/j.0962-1105.2003.00373.x
Source DB: PubMed Journal: J Sleep Res ISSN： 0962-1105 Impact factor: 3.981