Literature DB >> 14631354

Pharmacogenetics goes genomic.

David B Goldstein1, Sarah K Tate, Sanjay M Sisodiya.   

Abstract

Most people in the developed world will sooner or later be given prescription drugs to treat common diseases or to reduce the risk of getting them. Almost everyone who takes medicines will, at some stage, encounter those that do not work as well as they do in other people or even that cause an adverse reaction. Pharmacogenetics seeks to reduce the variation in how people respond to medicines by tailoring therapy to individual genetic make-up. It seems increasingly likely that investment in this field might be the most effective strategy for rapidly delivering the public health benefits that are promised by the Human Genome Project and related endeavours.

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Year:  2003        PMID: 14631354     DOI: 10.1038/nrg1229

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN: 1471-0056            Impact factor:   53.242


  53 in total

1.  Investigation of IVS14 + 1G > A polymorphism of DPYD gene in a group of Bosnian patients treated with 5-Fluorouracil and capecitabine.

Authors:  Timur Cerić; Nermina Obralić; Lejla Kapur-Pojskić; Drazenka Macić; Semir Beslija; Anes Pasić; Sejla Cerić
Journal:  Bosn J Basic Med Sci       Date:  2010-05       Impact factor: 3.363

2.  Racializing drug design: implications of pharmacogenomics for health disparities.

Authors:  Sandra Soo-Jin Lee
Journal:  Am J Public Health       Date:  2005-10-27       Impact factor: 9.308

3.  SNPselector: a web tool for selecting SNPs for genetic association studies.

Authors:  Hong Xu; Simon G Gregory; Elizabeth R Hauser; Judith E Stenger; Margaret A Pericak-Vance; Jeffery M Vance; Stephan Züchner; Michael A Hauser
Journal:  Bioinformatics       Date:  2005-09-22       Impact factor: 6.937

Review 4.  Genetics of drug resistance in epilepsy.

Authors:  Sanjay M Sisodiya
Journal:  Curr Neurol Neurosci Rep       Date:  2005-07       Impact factor: 5.081

Review 5.  The genetics of human drug response.

Authors:  David B Goldstein
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2005-08-29       Impact factor: 6.237

6.  Association mapping of Stagonospora nodorum blotch resistance in modern European winter wheat varieties.

Authors:  L Tommasini; T Schnurbusch; D Fossati; F Mascher; B Keller
Journal:  Theor Appl Genet       Date:  2007-07-19       Impact factor: 5.699

Review 7.  Pharmacogenomics and therapeutic prospects in dementia.

Authors:  Ramón Cacabelos
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2008-03       Impact factor: 5.270

Review 8.  Personalized medicine: is it a pharmacogenetic mirage?

Authors:  Rashmi R Shah; Devron R Shah
Journal:  Br J Clin Pharmacol       Date:  2012-10       Impact factor: 4.335

9.  The impact of individual and methodological factors in the variability of response to methylphenidate in ADHD pharmacogenetic studies from four different continents.

Authors:  Guilherme Polanczyk; Stephen V Faraone; Claiton H D Bau; Marcelo M Victor; Katja Becker; Reta Pelz; Jan K Buitelaar; Barbara Franke; Sandra Kooij; Emma van der Meulen; Keun-Ah Cheon; Eric Mick; Diane Purper-Ouakil; Philip Gorwood; Mark A Stein; Edwin H Cook; Luis Augusto Rohde
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2008-12-05       Impact factor: 3.568

10.  Improving the prediction of pharmacogenes using text-derived drug-gene relationships.

Authors:  Yael Garten; Nicholas P Tatonetti; Russ B Altman
Journal:  Pac Symp Biocomput       Date:  2010
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