Literature DB >> 14630388

Programmed cell death protein 4 (pdcd4): a novel target for antineoplastic therapy?

Brigitte Lankat-Buttgereit1, Rüdiger Göke.   

Abstract

Pdcd4 is a novel gene first identified as a differentially expressed protein during apoptosis. In the meantime not only the impact of Pdcd4 in programmed cell death but also an implication in transformation suppression by inhibition of protein translation is discussed. These features implicate a potential value of Pdcd4 as a molecular target in cancer therapy. This review summarizes the current knowledge about expression, structure and function of Pdcd4.

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Year:  2003        PMID: 14630388     DOI: 10.1016/j.biolcel.2003.09.003

Source DB:  PubMed          Journal:  Biol Cell        ISSN: 0248-4900            Impact factor:   4.458


  27 in total

1.  IL-10 -1082 SNP and IL-10 in primary CNS and vitreoretinal lymphomas.

Authors:  Hema L Ramkumar; De Fen Shen; Jingsheng Tuo; Rita M Braziel; Sarah E Coupland; Justine R Smith; Chi-Chao Chan
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2012-05-25       Impact factor: 3.117

2.  An essential role of PDCD4 in vascular smooth muscle cell apoptosis and proliferation: implications for vascular disease.

Authors:  Xiaojun Liu; Yunhui Cheng; Jian Yang; Thomas J Krall; Yuqing Huo; Chunxiang Zhang
Journal:  Am J Physiol Cell Physiol       Date:  2010-03-31       Impact factor: 4.249

3.  Initiation of sex change and gonadal gene expression in black sea bass (Centropristis striata) exposed to exemestane, an aromatase inhibitor.

Authors:  Timothy S Breton; Linas W Kenter; Katherine Greenlaw; Jacob Montgomery; Giles W Goetz; David L Berlinsky; J Adam Luckenbach
Journal:  Comp Biochem Physiol A Mol Integr Physiol       Date:  2018-11-09       Impact factor: 2.320

4.  Cycling exercise affects the expression of apoptosis-associated microRNAs after spinal cord injury in rats.

Authors:  Gang Liu; Benjamin E Keeler; Victoria Zhukareva; John D Houlé
Journal:  Exp Neurol       Date:  2010-09-16       Impact factor: 5.330

5.  Cryptocaryol Structure-Activity Relationship Study of Cancer Cell Cytotoxicity and Ability to Stabilize PDCD4.

Authors:  Michael F Cuccarese; Yanping Wang; Penny J Beuning; George A O'Doherty
Journal:  ACS Med Chem Lett       Date:  2014-02-17       Impact factor: 4.345

6.  Peroxisome proliferator-activated receptor-γ enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4.

Authors:  David E Green; Tamara C Murphy; Bum-Yong Kang; Brahmchetna Bedi; Zhihong Yuan; Ruxana T Sadikot; C Michael Hart
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2017-05-18       Impact factor: 5.464

7.  Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.

Authors:  Montserrat Soler-López; Andreas Zanzoni; Ricart Lluís; Ulrich Stelzl; Patrick Aloy
Journal:  Genome Res       Date:  2010-12-16       Impact factor: 9.043

8.  MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3.

Authors:  Florin M Selaru; Alexandru V Olaru; Takatsugu Kan; Stefan David; Yulan Cheng; Yuriko Mori; Jian Yang; Bogdan Paun; Zhe Jin; Rachana Agarwal; James P Hamilton; John Abraham; Christos Georgiades; Hector Alvarez; Perumal Vivekanandan; Wayne Yu; Anirban Maitra; Michael Torbenson; Paul J Thuluvath; Gregory J Gores; Nicholas F LaRusso; Ralph Hruban; Stephen J Meltzer
Journal:  Hepatology       Date:  2009-05       Impact factor: 17.425

9.  Antisense-miR-21 enhances differentiation/apoptosis and reduces cancer stemness state on anaplastic thyroid cancer.

Authors:  Vahid Haghpanah; Parviz Fallah; Rezvan Tavakoli; Mahmood Naderi; Hilda Samimi; Masoud Soleimani; Bagher Larijani
Journal:  Tumour Biol       Date:  2015-08-20

10.  Programmed cell death 4 mechanism of action: The model to be updated?

Authors:  Polina N Vikhreva; Svetlana V Kalinichenko; Igor V Korobko
Journal:  Cell Cycle       Date:  2017-08-30       Impact factor: 4.534

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