Literature DB >> 14630224

New magnetic resonance contrast agents as biochemical reporters.

Thomas J Meade1, Alisha K Taylor, Steven R Bull.   

Abstract

Magnetic resonance imaging is a noninvasive, volume rendering diagnostic technique that uses lanthanide complexes to enhance proton relaxation. Magnetic resonance imaging is not limited by light scattering as optical microscopic techniques are, and allows imaging of whole animals. Clinical contrast agents are nonspecific and report solely on anatomy, whereas contrast agents that can be activated can be tailored to report on the physiological status or metabolic activity of biological systems. These new classes of magnetic resonance contrast agents represent a substantial leap in the type of information that can be derived from imaging experiments, and are the focus of this review.

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Year:  2003        PMID： 14630224     DOI： 10.1016/j.conb.2003.09.009

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN： 0959-4388            Impact factor:   6.627


  17 in total

Review 1.  Molecular imaging perspectives.

Authors:  Paul J Cassidy; George K Radda
Journal:  J R Soc Interface       Date:  2005-06-22       Impact factor: 4.118

2.  Transcriptional response of Escherichia coli to TPEN.

Authors:  Tara K Sigdel; J Allen Easton; Michael W Crowder
Journal:  J Bacteriol       Date:  2006-09       Impact factor: 3.490

3.  Magnetically-assisted remote control (MARC) steering of endovascular catheters for interventional MRI: a model for deflection and design implications.

Authors:  Fabio Settecase; Marshall S Sussman; Mark W Wilson; Steven Hetts; Ronald L Arenson; Vincent Malba; Anthony F Bernhardt; Walter Kucharczyk; Timothy P L Roberts
Journal:  Med Phys       Date:  2007-08       Impact factor: 4.071

4.  Micelles obtained by aggregation of gemini surfactants containing the CCK8 peptide and a gadolinium complex.

Authors:  Antonella Accardo; Diego Tesauro; Anna Morisco; Gaetano Mangiapia; Mauro Vaccaro; Eliana Gianolio; Richard K Heenan; Luigi Paduano; Giancarlo Morelli
Journal:  J Biol Inorg Chem       Date:  2009-02-03       Impact factor: 3.358

Review 5.  Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signals.

Authors:  Hisataka Kobayashi; Michelle R Longmire; Mikako Ogawa; Peter L Choyke
Journal:  Chem Soc Rev       Date:  2011-05-23       Impact factor: 54.564

6.  A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model.

Authors:  Emily L Que; Elizabeth J New; Christopher J Chang
Journal:  Chem Sci       Date:  2012-04-18       Impact factor: 9.825

7.  A steroid-conjugated magnetic resonance probe enhances contrast in progesterone receptor expressing organs and tumors in vivo.

Authors:  Preeti A Sukerkar; Keith W MacRenaris; Thomas J Meade; Joanna E Burdette
Journal:  Mol Pharm       Date:  2011-07-08       Impact factor: 4.939

8.  A smart T(1)-weighted MRI contrast agent for uranyl cations based on a DNAzyme-gadolinium conjugate.

Authors:  Weichen Xu; Hang Xing; Yi Lu
Journal:  Analyst       Date:  2013-11-07       Impact factor: 4.616

9.  Synergistic enhancement of iron oxide nanoparticle and gadolinium for dual-contrast MRI.

Authors:  Fan Zhang; Xinglu Huang; Chunqi Qian; Lei Zhu; Naoki Hida; Gang Niu; Xiaoyuan Chen
Journal:  Biochem Biophys Res Commun       Date:  2012-08-07       Impact factor: 3.575

10.  Contrast-enhanced in vivo magnetic resonance microscopy of the mouse brain enabled by noninvasive opening of the blood-brain barrier with ultrasound.

Authors:  Gabriel P Howles; Kristin F Bing; Yi Qi; Stephen J Rosenzweig; Kathryn R Nightingale; G Allan Johnson
Journal:  Magn Reson Med       Date:  2010-10       Impact factor: 4.668
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