Literature DB >> 14622639

Patients' perspectives on statin therapy for treatment of hypercholesterolaemia: a qualitative study.

Elizabeth P Tolmie1, Grace M Lindsay, Susan M Kerr, Malcom R Brown, Ian Ford, Allan Gaw.   

Abstract

BACKGROUND: Health Care Practitioners' attempts to implement secondary prevention targets for coronary heart disease (CHD) may be restricted by low rates of persistence with statin therapy. There is a need to understand why some patients, despite having established CHD and elevated cholesterol, do not comply with their prescribed statin regimen. AIM: To explore patients' perspectives on compliance with statin therapy.
SETTING: Primary care, West of Scotland.
METHODS: The research approach was qualitative. Thirty-three patients prescribed statin therapy and identified as having different patterns of compliance (poor moderate and good) were interviewed. The in-depth interviews were conducted on a one to one basis. Patients prescribed statin therapy for less than three months were excluded. Data were analysed thematically with the assistance of QSR Nudist.
FINDINGS: From analysis of the narrative data, two broad categories, i.e. 'Patient-health care provider communication' and 'Health beliefs' were identified. These categories encompassed six main themes: 'Initiation of therapy'; 'Subsequent feedback'; 'Sources of misconceptions'; 'Unconditional acceptance'; 'Conditional acceptance'; 'Deferment and Rejection'. Acceptance of and compliance with statin therapy appeared to be associated with the provision, interpretation and feedback of information during patient-practitioner consultations, and patients' beliefs about personal health status, cholesterol, and recommended cholesterol-lowering strategies.
CONCLUSIONS: Patients' beliefs and understanding about cholesterol, and the role of cholesterol modifying strategies should be determined prior to the initiation of therapy and at appropriate intervals thereafter.

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Year:  2003        PMID: 14622639     DOI: 10.1016/S1474-5151(03)00028-8

Source DB:  PubMed          Journal:  Eur J Cardiovasc Nurs        ISSN: 1474-5151            Impact factor:   3.908


  13 in total

1.  Patients' perceptions of cholesterol, cardiovascular disease risk, and risk communication strategies.

Authors:  Roberta E Goldman; Donna R Parker; Charles B Eaton; Jeffrey M Borkan; Robert Gramling; Rebecca T Cover; David K Ahern
Journal:  Ann Fam Med       Date:  2006 May-Jun       Impact factor: 5.166

Review 2.  Knowledge, attitudes and beliefs of patients and carers regarding medication adherence: a review of qualitative literature.

Authors:  Maria Kelly; Suzanne McCarthy; Laura Jane Sahm
Journal:  Eur J Clin Pharmacol       Date:  2014-10-04       Impact factor: 2.953

3.  Patient beliefs and attitudes to taking statins: systematic review of qualitative studies.

Authors:  Angela Ju; Camilla S Hanson; Emily Banks; Rosemary Korda; Jonathan C Craig; Tim Usherwood; Peter MacDonald; Allison Tong
Journal:  Br J Gen Pract       Date:  2018-06       Impact factor: 5.386

Review 4.  Predictors of nonadherence to statins: a systematic review and meta-analysis.

Authors:  Devin M Mann; Mark Woodward; Paul Muntner; Louise Falzon; Ian Kronish
Journal:  Ann Pharmacother       Date:  2010-08-11       Impact factor: 3.154

Review 5.  Medication adherence in the older adults with chronic multimorbidity: a systematic review of qualitative studies on patient's experience.

Authors:  M Maffoni; S Traversoni; E Costa; L Midão; P Kardas; M Kurczewska-Michalak; A Giardini
Journal:  Eur Geriatr Med       Date:  2020-03-30       Impact factor: 1.710

6.  Statin use in Canadians: trends, determinants and persistence.

Authors:  C Ineke Neutel; Howard Morrison; Norm R C Campbell; Margaret de Groh
Journal:  Can J Public Health       Date:  2007 Sep-Oct

Review 7.  Medication taking in coronary artery disease: a systematic review and qualitative synthesis.

Authors:  Mohammed A Rashid; Duncan Edwards; Fiona M Walter; Jonathan Mant
Journal:  Ann Fam Med       Date:  2014 May-Jun       Impact factor: 5.166

8.  Predictors of medication adherence using a multidimensional adherence model in patients with heart failure.

Authors:  Jia-Rong Wu; Debra K Moser; Misook L Chung; Terry A Lennie
Journal:  J Card Fail       Date:  2008-05-27       Impact factor: 5.712

9.  Structural equation modeling of the proximal-distal continuum of adherence drivers.

Authors:  Colleen A McHorney; Ning Jackie Zhang; Timothy Stump; Xiaoquan Zhao
Journal:  Patient Prefer Adherence       Date:  2012-11-09       Impact factor: 2.711

10.  Treatment Gap in the National Health-screening Program in Korea: Claim-based Follow-up of Statin Use for Sustained Hypercholesterolemia.

Authors:  Eunmi Ahn; Dong Wook Shin; Hyung-kook Yang; Jae Moon Yun; So Hyun Chun; Beomseok Suh; Hyejin Lee; Ki Young Son; BeLong Cho
Journal:  J Korean Med Sci       Date:  2015-08-13       Impact factor: 2.153

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