Literature DB >> 14618080

Primary angioplasty in acute myocardial infarction: does age or race matter?

Carol R Regueiro1, Nikita Gill, Alison Hart, Linda Crawshaw, Teresa Hentosz, Richard P Shannon.   

Abstract

PURPOSE: Recent data suggest substantial variations in the treatment of acute myocardial infarction based on age, race, gender and socioeconomic status. We evaluated the use of primary angioplasty (PA) in acute myocardial infarction (AMI) in elderly and minority patients treated at an urban, teaching hospital. SUBJECTS AND METHODS: We reviewed the records of 322 patients with AMI admitted to an urban, teaching hospital from 1997-2000. Our main outcome was PA in AMI. Secondary outcomes included use of post-infarction therapies. Univariate analysis was performed on the variables of interest, age and race, as well as all candidate variables.
RESULTS: Unadjusted analysis revealed that elderly and African-American patients were significantly less likely to receive PA for AMI, and post-infarction beta-blockers, (all p <.05). Other factors that had a significant negative impact on use of PA included do-not-resuscitate status, increasing acuity of presenting signs and symptoms, severity of illness, dementia and subendocardial infarcts (all p <.05). After adjustment for these potential confounders, increasing age remained inversely associated with both PA (p <.001), and use of standard post-myocardial infarction beta-blockers, (p <.05). Additionally, African-American patients in our study were less likely to undergo PA as initial AMI (p <.01).
CONCLUSIONS: Our results indicate differences in the use of PA in the elderly and African-Americans. These differences are not explained by severity of illness and suggest that interventions and standard therapies may be withheld from those who may benefit most.

Entities:  

Keywords:  Empirical Approach; Health Care and Public Health

Mesh:

Year:  2003        PMID: 14618080     DOI: 10.1023/b:thro.0000003326.00180.60

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  34 in total

1.  Thrombolytic therapy in older patients.

Authors:  A K Berger; M J Radford; Y Wang; H M Krumholz
Journal:  J Am Coll Cardiol       Date:  2000-08       Impact factor: 24.094

2.  Race, sex, poverty, and the medical treatment of acute myocardial infarction in the elderly.

Authors:  S S Rathore; A K Berger; K P Weinfurt; M Feinleib; W J Oetgen; B J Gersh; K A Schulman
Journal:  Circulation       Date:  2000-08-08       Impact factor: 29.690

3.  Sex differences in the management of coronary artery disease. Survival and Ventricular Enlargement Investigators.

Authors:  R M Steingart; M Packer; P Hamm; M E Coglianese; B Gersh; E M Geltman; J Sollano; S Katz; L Moyé; L L Basta
Journal:  N Engl J Med       Date:  1991-07-25       Impact factor: 91.245

4.  The risks of risk adjustment.

Authors:  L I Iezzoni
Journal:  JAMA       Date:  1997-11-19       Impact factor: 56.272

5.  Thrombolytic therapy for eligible elderly patients with acute myocardial infarction.

Authors:  H M Krumholz; J E Murillo; J Chen; V Vaccarino; M J Radford; E F Ellerbeck; Y Wang
Journal:  JAMA       Date:  1997-06-04       Impact factor: 56.272

6.  Relation of race and sex to the use of reperfusion therapy in Medicare beneficiaries with acute myocardial infarction.

Authors:  J G Canto; J J Allison; C I Kiefe; C Fincher; R Farmer; P Sekar; S Person; N W Weissman
Journal:  N Engl J Med       Date:  2000-04-13       Impact factor: 91.245

7.  Racial variation in cardiac procedure use and survival following acute myocardial infarction in the Department of Veterans Affairs.

Authors:  E D Peterson; S M Wright; J Daley; G E Thibault
Journal:  JAMA       Date:  1994-04-20       Impact factor: 56.272

8.  Gender-related differences in reperfusion treatment allocation and outcome for acute myocardial infarction.

Authors:  J L Vacek; L R Handlin; T L Rosamond; G Beauchamp
Journal:  Am J Cardiol       Date:  1995-08-01       Impact factor: 2.778

9.  Analysis of prehospital delay among inner-city patients with symptoms of myocardial infarction: implications for therapeutic intervention.

Authors:  L T Clark; S V Bellam; A H Shah; J G Feldman
Journal:  J Natl Med Assoc       Date:  1992-11       Impact factor: 1.798

10.  Gender differences in reported symptoms for acute myocardial infarction: impact on prehospital delay time interval.

Authors:  H Meischke; M P Larsen; M S Eisenberg
Journal:  Am J Emerg Med       Date:  1998-07       Impact factor: 2.469

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  3 in total

1.  Neighborhood socioeconomic and racial disparities in angiography and coronary revascularization: the ARIC surveillance study.

Authors:  Kathryn M Rose; Randi E Foraker; Gerardo Heiss; Wayne D Rosamond; Chirayath M Suchindran; Eric A Whitsel
Journal:  Ann Epidemiol       Date:  2012-07-17       Impact factor: 3.797

Review 2.  Racism and Cardiology: A Global Call to Action.

Authors:  Shrilla Banerjee; F Aaysha Cader; Martha Gulati; Quinn Capers
Journal:  CJC Open       Date:  2021-09-24

3.  Underinvestigation and undertreatment of carotid disease in elderly patients with transient ischaemic attack and stroke: comparative population based study.

Authors:  Jack F Fairhead; Peter M Rothwell
Journal:  BMJ       Date:  2006-07-18
  3 in total

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