Suk J Moon1, William F Mieler. 1. Cullen Eye Institute, Baylor College of Medicine, Houston, Texas 77030, USA.
Abstract
PURPOSE OF REVIEW: A review is presented of the current literature on retinal complications of bone marrow and solid organ transplantation. RECENT FINDINGS: Retinal complications of bone marrow and solid organ transplantation include microvascular retinopathy, infection, and hemorrhagic findings. Other clinical observations include central serous chorioretinopathy, bilateral optic disc edema, and cyclosporine-related retinal toxicity. The cause of these clinical findings is likely to be multifactorial, resulting from the combined effects of cyclosporine, total body irradiation, infections, high-dose chemotherapy, and recurrent malignancies. SUMMARY: Understanding of these clinical entities of the posterior segment is important in minimizing the potentially sight-threatening complications from bone marrow and solid organ transplantation.
PURPOSE OF REVIEW: A review is presented of the current literature on retinal complications of bone marrow and solid organ transplantation. RECENT FINDINGS: Retinal complications of bone marrow and solid organ transplantation include microvascular retinopathy, infection, and hemorrhagic findings. Other clinical observations include central serous chorioretinopathy, bilateral optic disc edema, and cyclosporine-related retinal toxicity. The cause of these clinical findings is likely to be multifactorial, resulting from the combined effects of cyclosporine, total body irradiation, infections, high-dose chemotherapy, and recurrent malignancies. SUMMARY: Understanding of these clinical entities of the posterior segment is important in minimizing the potentially sight-threatening complications from bone marrow and solid organ transplantation.
Authors: Brian T Chan-Kai; Steven Yeh; Richard G Weleber; Peter J Francis; Grazyna Adamus; S Robert Witherspoon; Andreas K Lauer Journal: Clin Ophthalmol Date: 2010-07-30
Authors: Elon H C van Dijk; Darius Soonawala; Vera Rooth; Carel B Hoyng; Onno C Meijer; Aiko P J de Vries; Camiel J F Boon Journal: Graefes Arch Clin Exp Ophthalmol Date: 2017-10-23 Impact factor: 3.117