Literature DB >> 14613166

A metallopeptide assembly of the HIV-1 gp41 coiled coil is an ideal receptor in fluorescence detection of ligand binding.

Miriam Gochin1, Rodney Kiplin Guy, Martin A Case.   

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Year:  2003        PMID： 14613166     DOI： 10.1002/anie.200352006

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  13 in total

1.  A fluorescence assay for rapid detection of ligand binding affinity to HIV-1 gp41.

Authors:  Miriam Gochin; Ryan Savage; Spencer Hinckley; Lifeng Cai
Journal:  Biol Chem       Date:  2006-04       Impact factor: 3.915

2.  A novel fluorescence intensity screening assay identifies new low-molecular-weight inhibitors of the gp41 coiled-coil domain of human immunodeficiency virus type 1.

Authors:  Lifeng Cai; Miriam Gochin
Journal:  Antimicrob Agents Chemother       Date:  2007-04-23       Impact factor: 5.191

3.  A suite of modular fluorescence assays interrogate the human immunodeficiency virus glycoprotein-41 coiled coil and assist in determining binding mechanism of low molecular weight fusion inhibitors.

Authors:  Miriam Gochin
Journal:  Assay Drug Dev Technol       Date:  2012-08-16       Impact factor: 1.738

4.  Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library.

Authors:  Landon R Whitby; Kristopher E Boyle; Lifeng Cai; Xiaoqian Yu; Miriam Gochin; Dale L Boger
Journal:  Bioorg Med Chem Lett       Date:  2012-03-03       Impact factor: 2.823

5.  Paramagnetic relaxation assisted docking of a small indole compound in the HIV-1 gp41 hydrophobic pocket.

Authors:  Miriam Gochin; Guangyan Zhou; Aaron H Phillips
Journal:  ACS Chem Biol       Date:  2011-01-07       Impact factor: 5.100

Review 6.  Development of Small-molecule HIV Entry Inhibitors Specifically Targeting gp120 or gp41.

Authors:  Lu Lu; Fei Yu; Lifeng Cai; Asim K Debnath; Shibo Jiang
Journal:  Curr Top Med Chem       Date:  2016       Impact factor: 3.295

7.  The role of amphiphilicity and negative charge in glycoprotein 41 interactions in the hydrophobic pocket.

Authors:  Miriam Gochin; Lifeng Cai
Journal:  J Med Chem       Date:  2009-07-23       Impact factor: 7.446

8.  NMR-assisted computational studies of peptidomimetic inhibitors bound in the hydrophobic pocket of HIV-1 glycoprotein 41.

Authors:  Miriam Gochin; Landon R Whitby; Aaron H Phillips; Dale L Boger
Journal:  J Comput Aided Mol Des       Date:  2013-07-27       Impact factor: 3.686

9.  Stable extended human immunodeficiency virus type 1 gp41 coiled coil as an effective target in an assay for high-affinity fusion inhibitors.

Authors:  Lifeng Cai; Edina Balogh; Miriam Gochin
Journal:  Antimicrob Agents Chemother       Date:  2009-04-13       Impact factor: 5.191

10.  Identification of fragments targeting an alternative pocket on HIV-1 gp41 by NMR screening and similarity searching.

Authors:  Shidong Chu; Miriam Gochin
Journal:  Bioorg Med Chem Lett       Date:  2013-07-22       Impact factor: 2.823
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