Literature DB >> 14609843

In vitro and in vivo study of lens refilling with poloxamer hydrogel.

Y K Han1, J W Kwon, J S Kim, C-S Cho, W R Wee, J H Lee.   

Abstract

AIM: To evaluate the compatibility of poloxamer hydrogel as a material for an injectable intraocular lens, in vivo and in vitro.
METHODS: The appropriate concentration of poloxamer hydrogel was determined for injection by examining the transparency and gelling temperature of this material, assessing the lens capsule refilling technique, and studying the postoperative findings in a rabbit model.
RESULTS: Poloxamer hydrogel showed excellent transparency and 25% was identified as an appropriate concentration for the lens refilling material. The authors developed a technique for injecting the material in vivo and obtained excellent short term results.
CONCLUSIONS: Poloxamer hydrogel was identified as an appropriate material for direct lens refilling, and the developed injection technique produced excellent short term results.

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Year:  2003        PMID: 14609843      PMCID: PMC1771873          DOI: 10.1136/bjo.87.11.1399

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  18 in total

1.  rhEGF/HP-beta-CD complex in poloxamer gel for ophthalmic delivery.

Authors:  Eun Young Kim; Zhong Gao Gao; Jeong Sook Park; Hong Li; Kun Han
Journal:  Int J Pharm       Date:  2002-02-21       Impact factor: 5.875

2.  Refilling the lens with a inflatable endocapsular balloon: surgical procedure in animal eyes.

Authors:  O Nishi; T Hara; T Hara; Y Sakka; F Hayashi; K Nakamae; Y Yamada
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

3.  Effect of a composite membrane of chitosan and poloxamer gel on postoperative adhesive interactions.

Authors:  A Vlahos; P Yu; C E Lucas; A M Ledgerwood
Journal:  Am Surg       Date:  2001-01       Impact factor: 0.688

4.  Accommodation of an endocapsular silicone lens (Phaco-Ersatz) in the nonhuman primate.

Authors:  E Haefliger; J M Parel; F Fantes; E W Norton; D R Anderson; R K Forster; E Hernandez; W J Feuer
Journal:  Ophthalmology       Date:  1987-05       Impact factor: 12.079

5.  Lens refilling and endocapsular polymerization of an injectable intraocular lens: in vitro and in vivo study of potential risks and benefits.

Authors:  H J Hettlich; K Lucke; M N Asiyo-Vogel; M Schulte; A Vogel
Journal:  J Cataract Refract Surg       Date:  1994-03       Impact factor: 3.351

6.  Amplitudes of accommodation of primate lenses refilled with two types of inflatable endocapsular balloons.

Authors:  O Nishi; Y Nakai; Y Yamada; Y Mizumoto
Journal:  Arch Ophthalmol       Date:  1993-12

7.  Complications associated with endocapsular balloon implantation in rabbit eyes.

Authors:  T Hara; Y Sakka; K Sakanishi; Y Yamada; K Nakamae; F Hayashi
Journal:  J Cataract Refract Surg       Date:  1994-09       Impact factor: 3.351

8.  Refilling the lens of the rabbit eye after intercapsular cataract surgery using an endocapsular balloon and an anterior capsule suturing technique.

Authors:  O Nishi
Journal:  J Cataract Refract Surg       Date:  1989-07       Impact factor: 3.351

9.  The ability of poloxamers to inhibit platelet aggregation depends on their physicochemical properties.

Authors:  F Ahmed; P Alexandridis; H Shankaran; S Neelamegham
Journal:  Thromb Haemost       Date:  2001-12       Impact factor: 5.249

10.  Lens refilling with injectable silicone in rabbit eyes.

Authors:  O Nishi; K Nishi; C Mano; M Ichihara; T Honda
Journal:  J Cataract Refract Surg       Date:  1998-07       Impact factor: 3.351

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  2 in total

1.  Safety data on in situ gelling bimatoprost loaded nanovesicular formulations.

Authors:  Monika Yadav; Ana Guzman-Aranguez; Maria J Perez de Lara; Mandeep Singh; Joga Singh; Indu Pal Kaur
Journal:  Data Brief       Date:  2019-08-06

Review 2.  Recent Advances of Intraocular Lens Materials and Surface Modification in Cataract Surgery.

Authors:  Chenqi Luo; Hanle Wang; Xinyi Chen; Jingjie Xu; Houfa Yin; Ke Yao
Journal:  Front Bioeng Biotechnol       Date:  2022-06-08
  2 in total

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