Literature DB >> 14605183

Association of cytolethal distending toxin locus cdtB with enteropathogenic Escherichia coli isolated from patients with acute diarrhea in Calcutta, India.

Mritunjay Pandey1, Asis Khan, Suresh C Das, Bhaswati Sarkar, Soumen Kahali, Subhra Chakraborty, Santanu Chattopadhyay, Shinji Yamasaki, Yoshifumi Takeda, G Balakrish Nair, T Ramamurthy.   

Abstract

Among Escherichia coli strains isolated from stool specimens from patients with acute diarrhea, 1.4% were found to harbor cdtB by use of enrichment cytolethal distending toxin (CDT) PCR. These isolates were identified as being enteropathogenic E. coli (EPEC). In a retrospective study using a probe hybridization assay, 6 of 138 EPEC strains were found to harbor the cdtB locus. cdtB-positive isolates mostly belong to the O86a and O127a serogroups, with the former being associated with higher expression of CDT. Pulsed-field gel electrophoresis profiles showed that the EPEC strains harboring cdtB strains are genetically diverse.

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Year:  2003        PMID: 14605183      PMCID: PMC262502          DOI: 10.1128/JCM.41.11.5277-5281.2003

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  28 in total

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