Literature DB >> 14604659

Synthesis and cytotoxicity of 5-fluorouracil/diazeniumdiolate conjugates.

Tingwei Bill Cai1, Xiaoping Tang, Janet Nagorski, Paul G Brauschweiger, Peng George Wang.   

Abstract

5-Fluorouracil/diazeniumdiolate conjugates were first synthesized, and showed greater cytotoxicities than 5-fluorouracil for DU 145 human prostate and HeLa cancer cells.

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Year:  2003        PMID: 14604659     DOI: 10.1016/j.bmc.2003.09.003

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  9 in total

Review 1.  Recent developments in nitric oxide donor drugs.

Authors:  M R Miller; I L Megson
Journal:  Br J Pharmacol       Date:  2007-04-02       Impact factor: 8.739

2.  Synthesis and bioevaluation of 5-fluorouracil derivatives.

Authors:  Zhi-Yong Tian; Gang-Jun Du; Song-Qiang Xie; Jin Zhao; Wen-Yuan Gao; Chao-Jie Wang
Journal:  Molecules       Date:  2007-11-06       Impact factor: 4.411

3.  Synthesis and biological evaluation of new 4beta-5-Fu-substituted 4'-demethylepipodophyllotoxin derivatives.

Authors:  Fu-Min Zhang; Xiao-Jun Yao; Xuan Tian; Yong-Qiang Tu
Journal:  Molecules       Date:  2006-11-02       Impact factor: 4.411

Review 4.  Recent advances on endogenous gasotransmitters in inflammatory dermatological disorders.

Authors:  Lian Wang; Xin Xie; Bowen Ke; Wei Huang; Xian Jiang; Gu He
Journal:  J Adv Res       Date:  2021-09-01       Impact factor: 12.822

5.  Nitric oxide generating/releasing materials.

Authors:  Hongying Liang; Parimala Nacharaju; Adam Friedman; Joel M Friedman
Journal:  Future Sci OA       Date:  2015

6.  Synthesis and biological evaluation of new 5-fluorouracil-substituted ampelopsin derivatives.

Authors:  Wei-Ming Zhou; Rong-Rong He; Jian-Tao Ye; Na Zhang; De-Yu Liu
Journal:  Molecules       Date:  2010-03-24       Impact factor: 4.411

7.  Design, synthesis and biological evaluation of novel nitric oxide-donating podophyllotoxin derivatives as potential antiproliferative agents against multi-drug resistant leukemia cells.

Authors:  Lei Zhang; Ying Rong; Jie Zheng; Chengli Yang; Yongzheng Chen; Jing Wang; Gang Wei
Journal:  RSC Adv       Date:  2018-10-05       Impact factor: 3.361

8.  Combination of betulinic acid with diazen-1-ium-1,2-diolate nitric oxide moiety donating a novel anticancer candidate.

Authors:  Laiyin Zhang; Shuangxing Hou; Bo Li; Jianjian Pan; Liping Jiang; Guiying Zhou; Hong Gu; Caixing Zhao; Huiping Lu; Fenfen Ma
Journal:  Onco Targets Ther       Date:  2018-01-15       Impact factor: 4.147

9.  Folate Conjugated Polyethylene Glycol Probe for Tumor-Targeted Drug Delivery of 5-Fluorouracil.

Authors:  Shabnam Sarwar; Muhammad Abdul Qadir; Rima D Alharthy; Mahmood Ahmed; Saghir Ahmad; Michiel Vanmeert; Muhammad Usman Mirza; Abdul Hameed
Journal:  Molecules       Date:  2022-03-09       Impact factor: 4.411

  9 in total

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