Literature DB >> 14604081

Onchocerciasis (river blindness).

Lance H Borup1, John S Peters, Christopher R Sartori.   

Abstract

A 37-year-old African man presented for excision of a dermal nodule after a diagnosis of ocular onchocerciasis (river blindness). A nodule from the patient's left buttock contained several adult filarial worms, and results from adjacent skin biopsy specimens revealed numerous dermal microfilariae. The patient was admitted to the hospital and treated with one dose of ivermectin. Recommendations were made for ivermectin treatments every 6 months for up to 10 years. The history, clinical presentation, diagnosis, and treatment of onchocerciasis are discussed.

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Year:  2003        PMID： 14604081

Source DB:  PubMed          Journal:  Cutis        ISSN： 0011-4162


  9 in total

1.  An isothermal DNA amplification method for detection of Onchocerca volvulus infection in skin biopsies.

Authors:  Ole Lagatie; Michelle Merino; Linda Batsa Debrah; Alexander Y Debrah; Lieven J Stuyver
Journal:  Parasit Vectors       Date:  2016-12-01       Impact factor: 3.876

2.  Identification of three immunodominant motifs with atypical isotype profile scattered over the Onchocerca volvulus proteome.

Authors:  Ole Lagatie; Bieke Van Dorst; Lieven J Stuyver
Journal:  PLoS Negl Trop Dis       Date:  2017-01-26

3.  Plasma-derived parasitic microRNAs have insufficient concentrations to be used as diagnostic biomarker for detection of Onchocerca volvulus infection or treatment monitoring using LNA-based RT-qPCR.

Authors:  Ole Lagatie; Linda Batsa Debrah; Alex Debrah; Lieven J Stuyver
Journal:  Parasitol Res       Date:  2017-01-22       Impact factor: 2.289

4.  Evaluation of the Diagnostic Performance of Onchocerca volvulus Linear Epitopes in a Peptide Enzyme-Linked Immunosorbent Assay.

Authors:  Ole Lagatie; Ann Verheyen; Erik Nijs; Bieke Van Dorst; Linda Batsa Debrah; Alex Debrah; Taniawati Supali; Erliyani Sartono; Lieven J Stuyver
Journal:  Am J Trop Med Hyg       Date:  2018-01-04       Impact factor: 2.345

Review 5.  MicroRNAs in Ocular Infection.

Authors:  Shunbin Xu; Linda D Hazlett
Journal:  Microorganisms       Date:  2019-09-17

6.  Major antigen and paramyosin proteins as candidate biomarkers for serodiagnosis of canine infection by zoonotic Onchocerca lupi.

Authors:  Maria Stefania Latrofa; Giuseppe Palmisano; Giada Annoscia; Ciro Leonardo Pierri; Ramaswamy Chandrashekar; Domenico Otranto
Journal:  PLoS Negl Trop Dis       Date:  2021-02-10

7.  Evaluation of the diagnostic potential of urinary N-Acetyltyramine-O,β-glucuronide (NATOG) as diagnostic biomarker for Onchocerca volvulus infection.

Authors:  Ole Lagatie; Emmanuel Njumbe Ediage; Linda Batsa Debrah; Luc Diels; Christ Nolten; Petra Vinken; Alex Debrah; Lieve Dillen; Steven Silber; Lieven J Stuyver
Journal:  Parasit Vectors       Date:  2016-05-23       Impact factor: 3.876

8.  Linear epitopes in Onchocerca volvulus vaccine candidate proteins and excretory-secretory proteins.

Authors:  Ole Lagatie; Ann Verheyen; Bieke Van Dorst; Linda Batsa Debrah; Alex Debrah; Lieven J Stuyver
Journal:  Parasite Immunol       Date:  2018-10-08       Impact factor: 2.280

9.  Assessment of multiplex Onchocerca volvulus peptide ELISA in non-endemic tropical regions.

Authors:  Ole Lagatie; Elodie Granjon; Maurice R Odiere; Maan Zrein; Lieven J Stuyver
Journal:  Parasit Vectors       Date:  2019-11-29       Impact factor: 3.876
  9 in total

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