Literature DB >> 14597705

Cytochrome P450 flexibility.

Thomas L Poulos1.   

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Year:  2003        PMID: 14597705      PMCID: PMC263725          DOI: 10.1073/pnas.2336095100

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  15 in total

1.  Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus.

Authors:  J K Yano; L S Koo; D J Schuller; H Li; P R Ortiz de Montellano; T L Poulos
Journal:  J Biol Chem       Date:  2000-10-06       Impact factor: 5.157

2.  Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors.

Authors:  L M Podust; T L Poulos; M R Waterman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

3.  Pivotal role of water in the mechanism of P450BM-3.

Authors:  D C Haines; D R Tomchick; M Machius; J A Peterson
Journal:  Biochemistry       Date:  2001-11-13       Impact factor: 3.162

4.  Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties.

Authors:  Sam-Yong Park; Kazuhide Yamane; Shin-ichi Adachi; Yoshitsugu Shiro; Kara E Weiss; Shelley A Maves; Stephen G Sligar
Journal:  J Inorg Biochem       Date:  2002-09-20       Impact factor: 4.155

5.  The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid.

Authors:  H Li; T L Poulos
Journal:  Nat Struct Biol       Date:  1997-02

6.  Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding.

Authors:  J Cosme; E F Johnson
Journal:  J Biol Chem       Date:  2000-01-28       Impact factor: 5.157

7.  The role of mixed function oxidases in kaurene metabolism in Echinocystis macrocarpa Greene endosperm.

Authors:  P J Murphy; C A West
Journal:  Arch Biochem Biophys       Date:  1969-09       Impact factor: 4.013

8.  An open conformation of mammalian cytochrome P450 2B4 at 1.6-A resolution.

Authors:  Emily E Scott; You Ai He; Michael R Wester; Mark A White; Christopher C Chin; James R Halpert; Eric F Johnson; C David Stout
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-16       Impact factor: 11.205

9.  Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity.

Authors:  P A Williams; J Cosme; V Sridhar; E F Johnson; D E McRee
Journal:  Mol Cell       Date:  2000-01       Impact factor: 17.970

10.  Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding.

Authors:  Michael R Wester; Eric F Johnson; Cristina Marques-Soares; Sylvie Dijols; Patrick M Dansette; Daniel Mansuy; C David Stout
Journal:  Biochemistry       Date:  2003-08-12       Impact factor: 3.162

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  39 in total

1.  Substrate preferences and catalytic parameters determined by structural characteristics of sterol 14alpha-demethylase (CYP51) from Leishmania infantum.

Authors:  Tatiana Y Hargrove; Zdzislaw Wawrzak; Jialin Liu; W David Nes; Michael R Waterman; Galina I Lepesheva
Journal:  J Biol Chem       Date:  2011-05-31       Impact factor: 5.157

2.  Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.

Authors:  Lian-Hua Xu; Shinya Fushinobu; Satoshi Takamatsu; Takayoshi Wakagi; Haruo Ikeda; Hirofumi Shoun
Journal:  J Biol Chem       Date:  2010-04-07       Impact factor: 5.157

Review 3.  Substrate binding to cytochromes P450.

Authors:  Emre M Isin; F Peter Guengerich
Journal:  Anal Bioanal Chem       Date:  2008-07-13       Impact factor: 4.142

Review 4.  Modeling kinetics of subcellular disposition of chemicals.

Authors:  Stefan Balaz
Journal:  Chem Rev       Date:  2009-05       Impact factor: 60.622

5.  Structural insights into the mechanism of the drastic changes in enzymatic activity of the cytochrome P450 vitamin D3 hydroxylase (CYP107BR1) caused by a mutation distant from the active site.

Authors:  Yoshiaki Yasutake; Tomoshi Kameda; Tomohiro Tamura
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2017-04-26       Impact factor: 1.056

6.  Coupled flexibility change in cytochrome P450cam substrate binding determined by neutron scattering, NMR, and molecular dynamics simulation.

Authors:  Yinglong Miao; Zheng Yi; Carey Cantrell; Dennis C Glass; Jerome Baudry; Nitin Jain; Jeremy C Smith
Journal:  Biophys J       Date:  2012-11-20       Impact factor: 4.033

7.  Active-site hydration and water diffusion in cytochrome P450cam: a highly dynamic process.

Authors:  Yinglong Miao; Jerome Baudry
Journal:  Biophys J       Date:  2011-09-20       Impact factor: 4.033

8.  Catalytic modulation of human cytochromes P450 17A1 and P450 11B2 by phospholipid.

Authors:  Hwei-Ming Peng; Chase Barlow; Richard J Auchus
Journal:  J Steroid Biochem Mol Biol       Date:  2018-03-13       Impact factor: 4.292

9.  How does the reductase help to regulate the catalytic cycle of cytochrome P450 3A4 using the conserved water channel?

Authors:  Dan Fishelovitch; Sason Shaik; Haim J Wolfson; Ruth Nussinov
Journal:  J Phys Chem B       Date:  2010-05-06       Impact factor: 2.991

10.  Theoretical characterization of substrate access/exit channels in the human cytochrome P450 3A4 enzyme: involvement of phenylalanine residues in the gating mechanism.

Authors:  Dan Fishelovitch; Sason Shaik; Haim J Wolfson; Ruth Nussinov
Journal:  J Phys Chem B       Date:  2009-10-01       Impact factor: 2.991

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