Literature DB >> 1459723

Smoking-related DNA adducts in human gastric cancers.

G W Dyke1, J L Craven, R Hall, R C Garner.   

Abstract

DNA was extracted from the tumour tissue of 26 patients (18 smokers, 8 non-smokers) undergoing surgery for gastric cancer, and analyzed for the presence of DNA adducts by the 32P-post-labelling method. Adducts were detected in all samples tested, and adduct levels ranged from 2 adducts/10(8) nucleotides to 60 adducts/10(8) nucleotides. In male subjects, adduct levels were significantly greater in the DNA of smokers than in that of non-smokers. These results support epidemiological data suggesting that smoking is a risk factor for gastric cancer.

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Year:  1992        PMID： 1459723     DOI： 10.1002/ijc.2910520602

Source DB:  PubMed          Journal:  Int J Cancer        ISSN： 0020-7136            Impact factor:   7.396


  12 in total

1.  The association of cigarette smoking with gastric cancer: the multiethnic cohort study.

Authors:  Abraham M Y Nomura; Lynne R Wilkens; Brian E Henderson; Meira Epplein; Laurence N Kolonel
Journal:  Cancer Causes Control       Date:  2011-10-29       Impact factor: 2.506

2.  Interaction models of CYP1A1, GSTM1 polymorphisms and tobacco smoking in intestinal gastric cancer.

Authors:  Jing Shen; Run-Tian Wang; Yao-Chu Xu; Li-Wei Wang; Xin-Ru Wang
Journal:  World J Gastroenterol       Date:  2005-10-14       Impact factor: 5.742

3.  DNA damage in the stomach after vagotomy measured by 32P-postlabelling.

Authors:  G W Dyke; J L Craven; R Hall; R C Garner
Journal:  Gut       Date:  1993-12       Impact factor: 23.059

4.  Molecular cancer epidemiology can predict risk.

Authors:  R C Garner; K Dingley; C M Dale
Journal:  BMJ       Date:  1995-01-14

5.  Alcohol and tobacco use in relation to gastric cancer: a prospective study of men in Shanghai, China.

Authors:  Kristin A Moy; Yunhua Fan; Renwei Wang; Yu-Tang Gao; Mimi C Yu; Jian-Min Yuan
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2010-08-10       Impact factor: 4.254

Review 6.  Molecular mechanisms underlying the action of carcinogens in gastric cancer with a glimpse into targeted therapy.

Authors:  Elham Patrad; Solmaz Khalighfard; Taghi Amiriani; Vahid Khori; Ali Mohammad Alizadeh
Journal:  Cell Oncol (Dordr)       Date:  2022-09-23       Impact factor: 7.051

7.  Associations of Duration, Intensity, and Quantity of Smoking With Risk of Gastric Intestinal Metaplasia.

Authors:  Aaron P Thrift; Andre G Jove; Yan Liu; Mimi C Tan; Hashem B El-Serag
Journal:  J Clin Gastroenterol       Date:  2022-01-01       Impact factor: 3.062

Review 8.  DNA adducts in human tissues: biomarkers of exposure to carcinogens in tobacco smoke.

Authors:  D H Phillips
Journal:  Environ Health Perspect       Date:  1996-05       Impact factor: 9.031

9.  Clinical risk assessment for gastric cancer in asymptomatic population after a health check-up: An individualized consideration of the risk factors.

Authors:  Yoo Mi Park; Jie-Hyun Kim; Su Jung Baik; Jae Jun Park; Young Hoon Youn; Hyojin Park
Journal:  Medicine (Baltimore)       Date:  2016-11       Impact factor: 1.889

10.  Mass spectrometric profiling of DNA adducts in the human stomach associated with damage from environmental factors.

Authors:  Ippei Ohnishi; Yuji Iwashita; Yuto Matsushita; Shunsuke Ohtsuka; Takashi Yamashita; Keisuke Inaba; Atsuko Fukazawa; Hideto Ochiai; Keigo Matsumoto; Nobuhito Kurono; Yoshitaka Matsushima; Hiroki Mori; Shioto Suzuki; Shohachi Suzuki; Fumihiko Tanioka; Haruhiko Sugimura
Journal:  Genes Environ       Date:  2021-04-09
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