Literature DB >> 14587746

Palladium(II) acetate mediated oxidative cyclization of omega-unsaturated alpha-cyano ketones. A facile methylenecyclopentane annulation process.

Liang-Rern Kung1, Che-Hao Tu, Kak-Shan Shia, Hsing-Jang Liu.   

Abstract

A highly efficient methylenecyclopentane annulation process has been developed based on the Pd(II)-mediated oxidative cyclization of omega-unsaturated alpha-cyano ketones, readily accessed via the Michael addition of 3-butenylmagnesium bromide with 2-cyano-2-cycloalkenones.

Entities:  

Year:  2003        PMID: 14587746     DOI: 10.1039/b307114f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  A Copper-Mediated Conjugate Addition Approach to Analogues of Aconitine-Type Diterpenoid Alkaloids.

Authors:  Nicolle A Doering; Kevin G M Kou; Krissada Norseeda; Jack C Lee; Christopher J Marth; Gary M Gallego; Richmond Sarpong
Journal:  J Org Chem       Date:  2018-09-28       Impact factor: 4.354

  1 in total

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