Literature DB >> 14587519

Single-molecule visualization in cell biology.

Yasushi Sako1, Toshio Yanagida.   

Abstract

Recent progress in single-molecule detection techniques has allowed us to visualize the dynamic behaviour and reaction kinetics of individual biological molecules inside living cells. Single-molecule visualization provides a direct way to quantify, with a high spatial and temporal resolution, biological events inside cells at the single-molecule level. In this article, we discuss how single-molecule visualization can be used in cell biology.

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Year:  2003        PMID： 14587519

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  41 in total

1.  Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level.

Authors:  Raimund J Ober; Cruz Martinez; Xuming Lai; Jinchun Zhou; E Sally Ward
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-16       Impact factor: 11.205

Review 2.  Imaging gene expression in single living cells.

Authors:  Yaron Shav-Tal; Robert H Singer; Xavier Darzacq
Journal:  Nat Rev Mol Cell Biol       Date:  2004-10       Impact factor: 94.444

3.  Single-molecule tools elucidate H2A.Z nucleosome composition.

Authors:  Jiji Chen; Andrew Miller; Ann L Kirchmaier; Joseph M K Irudayaraj
Journal:  J Cell Sci       Date:  2012-03-05       Impact factor: 5.285

4.  Single-molecule analysis of epidermal growth factor binding on the surface of living cells.

Authors:  Yuji Teramura; Junya Ichinose; Hiroaki Takagi; Kenji Nishida; Toshio Yanagida; Yasushi Sako
Journal:  EMBO J       Date:  2006-08-31       Impact factor: 11.598

5.  Visualizing single molecules interacting with nuclear pore complexes by narrow-field epifluorescence microscopy.

Authors:  Weidong Yang; Siegfried M Musser
Journal:  Methods       Date:  2006-08       Impact factor: 3.608

6.  Intranuclear binding kinetics and mobility of single native U1 snRNP particles in living cells.

Authors:  David Grünwald; Beatrice Spottke; Volker Buschmann; Ulrich Kubitscheck
Journal:  Mol Biol Cell       Date:  2006-09-20       Impact factor: 4.138

7.  Tracking single Kinesin molecules in the cytoplasm of mammalian cells.

Authors:  Dawen Cai; Kristen J Verhey; Edgar Meyhöfer
Journal:  Biophys J       Date:  2007-03-30       Impact factor: 4.033

8.  Extending single molecule fluorescence observation time by amplitude-modulated excitation.

Authors:  Lydia Kisley; Wei-Shun Chang; David Cooper; Andrea P Mansur; Christy F Landes
Journal:  Methods Appl Fluoresc       Date:  2013-09-01       Impact factor: 3.009

9.  Single-molecule analysis of epidermal growth factor signaling that leads to ultrasensitive calcium response.

Authors:  Takeshi Uyemura; Hiroaki Takagi; Toshio Yanagida; Yasushi Sako
Journal:  Biophys J       Date:  2005-03-04       Impact factor: 4.033

10.  Photophysical properties of acene DCDHF fluorophores: long-wavelength single-molecule emitters designed for cellular imaging.

Authors:  Samuel J Lord; Zhikuan Lu; Hui Wang; Katherine A Willets; P James Schuck; Hsiao-lu D Lee; Stefanie Y Nishimura; Robert J Twieg; W E Moerner
Journal:  J Phys Chem A       Date:  2007-08-24       Impact factor: 2.781
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