Literature DB >> 14586103

Purification and identification of antimicrobial sesquiterpene lactones from yacon (Smallanthus sonchifolius) leaves.

Fengqiu Lin1, Morifumi Hasegawa, Osamu Kodama.   

Abstract

The extraction of yacon [Smallanthus sonchifolius (Poepp. and Endl.) H. Robinson; Asteraceae] leaves and chromatographic separation yielded two new antibacterial melampolide-type sesquiterpene lactones, 8beta-tigloyloxymelampolid-14-oic acid methyl ester and 8beta-methacryloyloxymelampolid-14-oic acid methyl ester, as well as the four known melampolides, sonchifolin, uvedalin, enhydrin and fluctuanin. The newly identified compound, 8beta-methacryloyloxymelampolid-14-oic acid methyl ester, exhibited potent antimicrobial activity against Bacillus subtilis and Pyricularia oryzae, while 8beta-tigloyloxymelampolid-14-oic acid methyl ester showed lower activity. Fluctuanin exhibited the strongest antibacterial activity against B. subtilis among these six sesquiterpene lactones.

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Year:  2003        PMID： 14586103     DOI： 10.1271/bbb.67.2154

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  8 in total

1.  Antibacterial and synergistic effects of Smallanthus sonchifolius leaf extracts against methicillin-resistant Staphylococcus aureus under light intensity.

Authors:  Hee Joung; Dong-Yeul Kwon; Jang-Gi Choi; Dong-Young Shin; Soon-Sil Chun; Young-Beob Yu; Dong-Won Shin
Journal:  J Nat Med       Date:  2010-01-30       Impact factor: 2.343

2.  The effect of yacon (Samallanthus sonchifolius) ethanol extract on cell proliferation and migration of C6 glioma cells stimulated with fetal bovine serum.

Authors:  Kang Pa Lee; Nan Hee Choi; Jin Teak Kim; In-Sik Park
Journal:  Nutr Res Pract       Date:  2015-03-06       Impact factor: 1.926

3.  Germacranolide-type sesquiterpene lactones from Smallanthus sonchifolius with promising activity against Leishmania mexicana and Trypanosoma cruzi.

Authors:  Jerónimo L Ulloa; Renata Spina; Agustina Casasco; Patricia B Petray; Virginia Martino; Miguel A Sosa; Fernanda M Frank; Liliana V Muschietti
Journal:  Parasit Vectors       Date:  2017-11-13       Impact factor: 3.876

4.  Metabolomic and Gene Expression Studies Reveal the Diversity, Distribution and Spatial Regulation of the Specialized Metabolism of Yacón (Smallanthus sonchifolius, Asteraceae).

Authors:  Guillermo F Padilla-González; Evelyn Amrehn; Maximilian Frey; Javier Gómez-Zeledón; Alevtina Kaa; Fernando B Da Costa; Otmar Spring
Journal:  Int J Mol Sci       Date:  2020-06-26       Impact factor: 5.923

5.  Antiviral Activity of Metabolites from Peruvian Plants against SARS-CoV-2: An In Silico Approach.

Authors:  Luis Daniel Goyzueta-Mamani; Haruna Luz Barazorda-Ccahuana; Karel Mena-Ulecia; Miguel Angel Chávez-Fumagalli
Journal:  Molecules       Date:  2021-06-25       Impact factor: 4.411

6.  Trypanocidal Activity of Smallanthus sonchifolius: Identification of Active Sesquiterpene Lactones by Bioassay-Guided Fractionation.

Authors:  F M Frank; J Ulloa; S I Cazorla; G Maravilla; E L Malchiodi; A Grau; V Martino; C Catalán; L V Muschietti
Journal:  Evid Based Complement Alternat Med       Date:  2013-06-06       Impact factor: 2.629

7.  Evaluation of Antioxidant, Antidiabetic and Anticholinesterase Activities of Smallanthus sonchifolius Landraces and Correlation with Their Phytochemical Profiles.

Authors:  Daniela Russo; Patrícia Valentão; Paula B Andrade; Eloy C Fernandez; Luigi Milella
Journal:  Int J Mol Sci       Date:  2015-07-31       Impact factor: 5.923

Review 8.  Phytochemical Properties and Nutrigenomic Implications of Yacon as a Potential Source of Prebiotic: Current Evidence and Future Directions.

Authors:  Yang Cao; Zheng Feei Ma; Hongxia Zhang; Yifan Jin; Yihe Zhang; Frank Hayford
Journal:  Foods       Date:  2018-04-12
  8 in total

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