| Literature DB >> 14585349 |
Abstract
A recent microarray-based study shows that Ras/Akt signaling rapidly alters the pattern of existing mRNAs that are recruited to polysomes. This response precedes the effects of transcription on total cellular RNA, suggesting that the primary effect of Ras/Akt signaling on gene expression may occur mainly at the level of translation.Entities:
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Year: 2003 PMID: 14585349 DOI: 10.1016/s1535-6108(03)00247-2
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743