Literature DB >> 14584631

Fear-potentiated startle and posttraumatic stress symptoms in urban police officers.

Nnamdi Pole1, Thomas C Neylan, Suzanne R Best, Scott P Orr, Charles R Marmar.   

Abstract

We studied the effects of increasing threat conditions on self-reported emotion, eyeblink electromyogram, and skin conductance responses to startling sounds in 55 police officers who endorsed a range of PTSD (posttraumatic stress disorder) symptoms. We found that contextual threat affected both physiologic and self-reported emotional responses. Greater PTSD symptom severity was related to greater physiologic responses under the low and medium but not under the high threat condition. The relationship between PTSD symptoms and physiologic responses was neither explained by self-reported emotional responses nor preexisting reported exaggerated startle symptoms. Our results emphasize the importance of contextual threat and suggest that laboratory measures of startle improve upon self-reported exaggerated startle alone in indexing PTSD symptom severity in urban police officers.

Entities:  

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Year:  2003        PMID: 14584631     DOI: 10.1023/A:1025758411370

Source DB:  PubMed          Journal:  J Trauma Stress        ISSN: 0894-9867


  26 in total

Review 1.  Diagnostic Biomarkers for Posttraumatic Stress Disorder: Promising Horizons from Translational Neuroscience Research.

Authors:  Vasiliki Michopoulos; Seth Davin Norrholm; Tanja Jovanovic
Journal:  Biol Psychiatry       Date:  2015-01-30       Impact factor: 13.382

2.  The brain orexin system and almorexant in fear-conditioned startle reactions in the rat.

Authors:  Michel A Steiner; Hugues Lecourt; Francois Jenck
Journal:  Psychopharmacology (Berl)       Date:  2012-05-17       Impact factor: 4.530

3.  Emotion regulation and potentiated startle across affective picture and threat-of-shock paradigms.

Authors:  Shmuel Lissek; Kaebah Orme; Dana J McDowell; Linda L Johnson; David A Luckenbaugh; Johanna M Baas; Brian R Cornwell; Christian Grillon
Journal:  Biol Psychol       Date:  2007-07-13       Impact factor: 3.251

Review 4.  Linking dimensional models of internalizing psychopathology to neurobiological systems: affect-modulated startle as an indicator of fear and distress disorders and affiliated traits.

Authors:  Uma Vaidyanathan; Christopher J Patrick; Bruce N Cuthbert
Journal:  Psychol Bull       Date:  2009-11       Impact factor: 17.737

5.  Elevated responding to safe conditions as a specific risk factor for anxiety versus depressive disorders: evidence from a longitudinal investigation.

Authors:  Michelle G Craske; Kate B Wolitzky-Taylor; Susan Mineka; Richard Zinbarg; Allison M Waters; Suzanne Vrshek-Schallhorn; Alyssa Epstein; Bruce Naliboff; Edward Ornitz
Journal:  J Abnorm Psychol       Date:  2011-10-10

6.  Frequency and severity approaches to indexing exposure to trauma: the Critical Incident History Questionnaire for police officers.

Authors:  Daniel S Weiss; Alain Brunet; Suzanne R Best; Thomas J Metzler; Akiva Liberman; Nnamdi Pole; Jeffrey A Fagan; Charles R Marmar
Journal:  J Trauma Stress       Date:  2010-11-15

7.  Effects of Threat Context, Trauma History, and Posttraumatic Stress Disorder Status on Physiological Startle Reactivity in Gulf War Veterans.

Authors:  Andrea N Niles; Adam Luxenberg; Thomas C Neylan; Sabra S Inslicht; Anne Richards; Thomas J Metzler; Jennifer Hlavin; Jersey Deng; Aoife O'Donovan
Journal:  J Trauma Stress       Date:  2018-07-30

8.  Increased anxiety during anticipation of unpredictable aversive stimuli in posttraumatic stress disorder but not in generalized anxiety disorder.

Authors:  Christian Grillon; Daniel S Pine; Shmuel Lissek; Stephanie Rabin; Omer Bonne; Meena Vythilingam
Journal:  Biol Psychiatry       Date:  2009-02-12       Impact factor: 13.382

Review 9.  Phasic vs sustained fear in rats and humans: role of the extended amygdala in fear vs anxiety.

Authors:  Michael Davis; David L Walker; Leigh Miles; Christian Grillon
Journal:  Neuropsychopharmacology       Date:  2010-01       Impact factor: 7.853

10.  Startle response in behaviorally inhibited adolescents with a lifetime occurrence of anxiety disorders.

Authors:  Bethany C Reeb-Sutherland; Sarah M Helfinstein; Kathryn A Degnan; Koraly Pérez-Edgar; Heather A Henderson; Shmuel Lissek; Andrea Chronis-Tuscano; Christian Grillon; Daniel S Pine; Nathan A Fox
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2009-06       Impact factor: 8.829

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