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Literature DB >> 14583616

The use of isotope effects to determine enzyme mechanisms.

W Wallace Cleland¹.

Abstract

Mesh：

Substances：
Enzymes
Isotopes

Year: 2003 PMID： 14583616 DOI： 10.1074/jbc.X300005200

Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157

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Cited

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16 in total

Review 1. Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactions.

Authors: Jingzhi Pu; Jiali Gao; Donald G Truhlar
Journal: Chem Rev Date: 2006-08 Impact factor: 60.622

Review 2. H-transfers in Photosystem II: what can we learn from recent lessons in the enzyme community?

Authors: Sam Hay; Nigel S Scrutton
Journal: Photosynth Res Date: 2008-09-03 Impact factor: 3.573

3. Mechanistic insights into F₄₂₀-dependent glucose-6-phosphate dehydrogenase using isotope effects and substrate inhibition studies.

Authors: Mercy A Oyugi; Ghader Bashiri; Edward N Baker; Kayunta Johnson-Winters
Journal: Biochim Biophys Acta Proteins Proteom Date: 2017-08-12 Impact factor: 3.036

4. Kinetic isolation and characterization of the radical rearrangement step in coenzyme B12-dependent ethanolamine ammonia-lyase.

Authors: Chen Zhu; Kurt Warncke
Journal: J Am Chem Soc Date: 2010-07-21 Impact factor: 15.419

5. Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1.

Authors: Yoshihide Tokunou; Kazuhito Hashimoto; Akihiro Okamoto
Journal: J Vis Exp Date: 2018-04-16 Impact factor: 1.355

6. Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase.

Authors: Peter J Harrison; Kenneth Gable; Niranjanakumari Somashekarappa; Van Kelly; David J Clarke; James H Naismith; Teresa M Dunn; Dominic J Campopiano
Journal: J Lipid Res Date: 2019-02-21 Impact factor: 5.922

The use of isotope effects to determine enzyme mechanisms.

Review 1. Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactions.

Review 2. H-transfers in Photosystem II: what can we learn from recent lessons in the enzyme community?

3. Mechanistic insights into F₄₂₀-dependent glucose-6-phosphate dehydrogenase using isotope effects and substrate inhibition studies.

4. Kinetic isolation and characterization of the radical rearrangement step in coenzyme B12-dependent ethanolamine ammonia-lyase.

5. Electrochemical Detection of Deuterium Kinetic Isotope Effect on Extracellular Electron Transport in Shewanella oneidensis MR-1.

6. Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase.

7. Elucidating the unusual reaction kinetics of D-glucuronyl C5-epimerase.

8. Mechanism of Methyldehydrofosmidomycin Maturation: Use Olefination to Enable Chain Elongation.

9. Pinpointing dynamic coupling in enzymes for efficient drug design.

10. Different dynamical effects in mesophilic and hyperthermophilic dihydrofolate reductases.