Literature DB >> 145760

The methylation of DNA in regenerating rat liver.

T A Lawson.   

Abstract

There was more persistent methylation of liver DNA from rats given [14C]DMN if it was given during liver regeneration, either after partial hepatectomy or a dose of CCl4 compared to otherwise untreated rats. During liver regeneration, DMN metabolism was slowed making the active metabolites available for longer.

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Year:  1977        PMID： 145760     DOI： 10.1007/bf00285327

Source DB:  PubMed          Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol        ISSN： 0084-5353


  8 in total

1.  Phosphotriesters in rat liver deoxyribonucleic acid after the administration of the carcinogen NN-dimethylnitrosamine in vivo.

Authors:  P J O'Connor; G P Marigison; A W Craig
Journal:  Biochem J       Date:  1975-03       Impact factor: 3.857

2.  Effects of partial hepatectomy on carcinogenicity, metabolism, and binding to DNA of ethyl carbamate.

Authors:  A W Pound; T A Lawson
Journal:  J Natl Cancer Inst       Date:  1974-08       Impact factor: 13.506

3.  Liver carcinomas induced in rats by single administration of dimethylnitrosamine after partial hepatectomy.

Authors:  V M Craddock
Journal:  J Natl Cancer Inst       Date:  1971-10       Impact factor: 13.506

4.  An extension of the naphthalene disulphonate method for mammalian nucleic acids.

Authors:  J H Parish; K S Kirby
Journal:  Biochim Biophys Acta       Date:  1967-06-20

Review 5.  Carcinogenic nitroso compounds.

Authors:  P N Magee; J M Barnes
Journal:  Adv Cancer Res       Date:  1967       Impact factor: 6.242

6.  [A new method for the colorimetric determination of nitrosamines after cleavage of the N-nitroso-group with hydrogen bromide in glacial acetic acid].

Authors:  G Eisenbrand; R Preussmann
Journal:  Arzneimittelforschung       Date:  1970-10

7.  The interaction of ( 3 H)ethyl carbamate with nucleic acids of regenerating mouse liver.

Authors:  T A Lawson; A W Pound
Journal:  Chem Biol Interact       Date:  1972-04       Impact factor: 5.192

8.  Increased carcinogenic action of dimethylnitrosamine after prior administration of carbon tetrachloride.

Authors:  A W Pound; T A Lawson; L Horn
Journal:  Br J Cancer       Date:  1973-06       Impact factor: 7.640
  8 in total

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