Literature DB >> 14575649

Does tumor growth follow a "universal law"?

Caterina Guiot1, Piero Giorgio Degiorgis, Pier Paolo Delsanto, Pietro Gabriele, Thomas S Deisboeck.   

Abstract

A general model for the ontogenetic growth of living organisms has been recently proposed. Here we investigate the extension of this model to the growth of solid malignant tumors. A variety of in vitro and in vivo data are analysed and compared with the prediction of a "universal" law, relating properly rescaled tumor masses and tumor growth times. The results support the notion that tumor growth follows such a universal law. Several important implications of this finding are discussed, including its relevance for tumor metastasis and recurrence, cell turnover rates, angiogenesis and invasion.

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Year:  2003        PMID: 14575649     DOI: 10.1016/s0022-5193(03)00221-2

Source DB:  PubMed          Journal:  J Theor Biol        ISSN: 0022-5193            Impact factor:   2.691


  42 in total

1.  Using Fractal Geometry and Universal Growth Curves as Diagnostics for Comparing Tumor Vasculature and Metabolic Rate With Healthy Tissue and for Predicting Responses to Drug Therapies.

Authors:  Van M Savage; Alexander B Herman; Geoffrey B West; Kevin Leu
Journal:  Discrete Continuous Dyn Syst Ser B       Date:  2013-06       Impact factor: 1.327

2.  How to cluster gene expression dynamics in response to environmental signals.

Authors:  Yaqun Wang; Meng Xu; Zhong Wang; Ming Tao; Junjia Zhu; Li Wang; Runze Li; Scott A Berceli; Rongling Wu
Journal:  Brief Bioinform       Date:  2011-07-10       Impact factor: 11.622

3.  A mesoscopic simulator to uncover heterogeneity and evolutionary dynamics in tumors.

Authors:  Juan Jiménez-Sánchez; Álvaro Martínez-Rubio; Anton Popov; Julián Pérez-Beteta; Youness Azimzade; David Molina-García; Juan Belmonte-Beitia; Gabriel F Calvo; Víctor M Pérez-García
Journal:  PLoS Comput Biol       Date:  2021-02-10       Impact factor: 4.475

Review 4.  The dynamics of drug resistance: a mathematical perspective.

Authors:  Orit Lavi; Michael M Gottesman; Doron Levy
Journal:  Drug Resist Updat       Date:  2012-03-03       Impact factor: 18.500

5.  Estimating Tumor Growth Rates In Vivo.

Authors:  Anne Talkington; Rick Durrett
Journal:  Bull Math Biol       Date:  2015-10       Impact factor: 1.758

6.  Oscillations in growth of multicellular tumour spheroids: a revisited quantitative analysis.

Authors:  A S Gliozzi; C Guiot; R Chignola; P P Delsanto
Journal:  Cell Prolif       Date:  2010-08       Impact factor: 6.831

7.  Richards-like two species population dynamics model.

Authors:  Fabiano Ribeiro; Brenno Caetano Troca Cabella; Alexandre Souto Martinez
Journal:  Theory Biosci       Date:  2014-08-13       Impact factor: 1.919

Review 8.  In silico cancer modeling: is it ready for prime time?

Authors:  Thomas S Deisboeck; Le Zhang; Jeongah Yoon; Jose Costa
Journal:  Nat Clin Pract Oncol       Date:  2008-10-14

9.  Natural history, growth kinetics, and outcomes of untreated clinically localized renal tumors under active surveillance.

Authors:  Paul L Crispen; Rosalia Viterbo; Stephen A Boorjian; Richard E Greenberg; David Y T Chen; Robert G Uzzo
Journal:  Cancer       Date:  2009-07-01       Impact factor: 6.860

10.  Tumor growth instability and its implications for chemotherapy.

Authors:  Paolo Castorina; Daniela Carcò; Caterina Guiot; Thomas S Deisboeck
Journal:  Cancer Res       Date:  2009-10-27       Impact factor: 12.701

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