| Literature DB >> 14575516 |
Roger Hanselmann1, Jiacheng Zhou, Philip Ma, Pat N Confalone.
Abstract
Isoxazolidines have been synthesized in diastereomeric excess up to 94% via a MgBr2-induced chelation-controlled 1,3-dipolar cycloaddition reaction with N-hydroxyphenylglycinol as a chiral auxiliary. The diastereomerically pure isoxazolidines were further transformed into cyclic and acyclic beta-amino acid derivatives.Entities:
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Year: 2003 PMID： 14575516 DOI： 10.1021/jo034940o
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354