Literature DB >> 14575507

Head-to-tail oxime cyclization of oligodeoxynucleotides for the efficient synthesis of circular DNA analogues.

Om Prakash Edupuganti1, Eric Defrancq, Pascal Dumy.   

Abstract

A convenient strategy for the synthesis of the analogue of cyclic oligodeoxyribonucleotides is presented. The cyclization of the oligonucleotide was accomplished through intramolecular oxime bond formation between a 5'-oxyamine moiety and a 3'-aldehydic group.

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Year:  2003        PMID: 14575507     DOI: 10.1021/jo035064h

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

Review 1.  In vitro circularization of RNA.

Authors:  Sabine Müller; Bettina Appel
Journal:  RNA Biol       Date:  2016-09-26       Impact factor: 4.652

2.  Circular DNA and DNA/RNA hybrid molecules as scaffolds for ricin inhibitor design.

Authors:  Matthew B Sturm; Setu Roday; Vern L Schramm
Journal:  J Am Chem Soc       Date:  2007-04-07       Impact factor: 15.419

3.  Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight.

Authors:  Claudia Riccardi; Albert Meyer; Jean-Jacques Vasseur; Domenico Cavasso; Irene Russo Krauss; Luigi Paduano; François Morvan; Daniela Montesarchio
Journal:  Int J Mol Sci       Date:  2020-05-29       Impact factor: 5.923

  3 in total

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