Literature DB >> 14574521

The hydration dynamics of polyelectrolyte gels with applications to cell motility and drug delivery.

Charles W Wolgemuth1, Alexander Mogilner, George Oster.   

Abstract

We combine the physics of gels with the hydrodynamics of two-phase fluids to construct a set of equations that describe the hydration dynamics of polyelectrolyte gels. We use the model to address three problems. First, we express the effective diffusion constants for neutral and charged spherically distributed gels in terms of microscopic parameters. Second, we use the model to describe the locomotion of nematode sperm cells. Finally, we describe the swelling dynamics of polyelectrolyte gels used for drug release.

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Year:  2003        PMID: 14574521     DOI: 10.1007/s00249-003-0344-5

Source DB:  PubMed          Journal:  Eur Biophys J        ISSN: 0175-7571            Impact factor:   1.733


  13 in total

1.  A mixture theory for charged-hydrated soft tissues containing multi-electrolytes: passive transport and swelling behaviors.

Authors:  W Y Gu; W M Lai; V C Mow
Journal:  J Biomech Eng       Date:  1998-04       Impact factor: 2.097

2.  Mathematical modeling of diffusion-mediated release from bulk degrading matrices.

Authors:  A R Tzafriri
Journal:  J Control Release       Date:  2000-01-03       Impact factor: 9.776

3.  Reaction diffusion model of the enzymatic erosion of insoluble fibrillar matrices.

Authors:  Abraham R Tzafriri; Michel Bercovier; Hanna Parnas
Journal:  Biophys J       Date:  2002-08       Impact factor: 4.033

4.  Theory of pattern formation in gels: Surface folding in highly compressible elastic bodies.

Authors: 
Journal:  Phys Rev A Gen Phys       Date:  1989-06-01

5.  Spongelike domain structure in a two-dimensional model gel undergoing volume-phase transition.

Authors: 
Journal:  Phys Rev A Gen Phys       Date:  1989-05-01

6.  On the mechanics of the first cleavage division of the sea urchin egg.

Authors:  X He; M Dembo
Journal:  Exp Cell Res       Date:  1997-06-15       Impact factor: 3.905

7.  Traction forces in locomoting cells.

Authors:  T Oliver; M Dembo; K Jacobson
Journal:  Cell Motil Cytoskeleton       Date:  1995

8.  A triphasic theory for the swelling and deformation behaviors of articular cartilage.

Authors:  W M Lai; J S Hou; V C Mow
Journal:  J Biomech Eng       Date:  1991-08       Impact factor: 2.097

Review 9.  How nematode sperm crawl.

Authors:  Dean Bottino; Alexander Mogilner; Tom Roberts; Murray Stewart; George Oster
Journal:  J Cell Sci       Date:  2002-01-15       Impact factor: 5.285

Review 10.  Acting like actin. The dynamics of the nematode major sperm protein (msp) cytoskeleton indicate a push-pull mechanism for amoeboid cell motility.

Authors:  T M Roberts; M Stewart
Journal:  J Cell Biol       Date:  2000-04-03       Impact factor: 10.539

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  15 in total

1.  The motility of mollicutes.

Authors:  Charles W Wolgemuth; Oleg Igoshin; George Oster
Journal:  Biophys J       Date:  2003-08       Impact factor: 4.033

2.  Multiphase flow models of biogels from crawling cells to bacterial biofilms.

Authors:  N G Cogan; Robert D Guy
Journal:  HFSP J       Date:  2010-02-12

3.  An immersed boundary method for two-phase fluids and gels and the swimming of Caenorhabditis elegans through viscoelastic fluids.

Authors:  Pilhwa Lee; Charles W Wolgemuth
Journal:  Phys Fluids (1994)       Date:  2016-01-06       Impact factor: 3.521

4.  MSP dynamics drives nematode sperm locomotion.

Authors:  Charles W Wolgemuth; Long Miao; Orion Vanderlinde; Tom Roberts; George Oster
Journal:  Biophys J       Date:  2005-01-21       Impact factor: 4.033

5.  Lamellipodial contractions during crawling and spreading.

Authors:  Charles W Wolgemuth
Journal:  Biophys J       Date:  2005-07-08       Impact factor: 4.033

6.  Depolymerization-driven flow in nematode spermatozoa relates crawling speed to size and shape.

Authors:  Mark Zajac; Brian Dacanay; William A Mohler; Charles W Wolgemuth
Journal:  Biophys J       Date:  2008-01-28       Impact factor: 4.033

7.  Molecular simulation of the swelling of polyelectrolyte gels by monovalent and divalent counterions.

Authors:  De-Wei Yin; Ferenc Horkay; Jack F Douglas; Juan J de Pablo
Journal:  J Chem Phys       Date:  2008-10-21       Impact factor: 3.488

Review 8.  Design features of a mitotic spindle: balancing tension and compression at a single microtubule kinetochore interface in budding yeast.

Authors:  David C Bouck; Ajit P Joglekar; Kerry S Bloom
Journal:  Annu Rev Genet       Date:  2008       Impact factor: 16.830

9.  A Simple 1-D Physical Model for the Crawling Nematode Sperm Cell.

Authors:  A Mogilner; D W Verzi
Journal:  J Stat Phys       Date:  2003-03-01       Impact factor: 1.548

Review 10.  Mathematics of cell motility: have we got its number?

Authors:  Alex Mogilner
Journal:  J Math Biol       Date:  2008-05-07       Impact factor: 2.259

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