| Literature DB >> 14561514 |
Wisinee Chanmahasathien1, Yushan Li, Masayuki Satake, Yasukatsu Oshima, Nijsiri Ruangrungsi, Yasushi Ohizumi.
Abstract
Two prenylated xanthones, 1,4,5,6-tetrahydroxy-7,8-di(3-methylbut-2-enyl)xanthone (1) and 1,2,6-trihydroxy-5-methoxy-7-(3-methylbut-2-enyl)xanthone (2), were isolated from the wood of Garcinia xanthochymus along with a known xanthone, 12b-hydroxy-des-D-garcigerrin A (3). Their structures were elucidated by spectroscopic analysis. Compound 1 (10 muM), 2 (10-30 muM) and 3 (10 muM) showed a markedly enchancing activity of nerve growth factor (NGF)-mediated neurite outgrowth on PC12D cells.Entities:
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Year: 2003 PMID： 14561514 DOI： 10.1016/s0031-9422(03)00431-x
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072