Literature DB >> 14561480

New styryl sulfones as anticancer agents.

Manohar Sharma Vedula1, Aravind Babu Pulipaka, Chandrasekhar Venna, Vamsee Krishna Chintakunta, Sreenu Jinnapally, Venkata Adiseshu Kattuboina, Ravi Krishna Vallakati, Vishnu Basetti, Venkateswarlu Akella, Sriram Rajgopal, Ajaya Kumar Reka, Sravan Kumar Teepireddy, Prem Kumar Mamnoor, Ramanujam Rajagopalan, Gopalakrishnan Bulusu, Akash Khandelwal, Vijay V Upreti, Srinivas Rao Mamidi.   

Abstract

New styryl sulfone compounds have been synthesized and evaluated for their anti-proliferative activity. Among the compounds synthesized, one compound (7k) has shown 51% tumor growth inhibition in mice implanted with HT-29 human carcinoma at 400 mg kg(-1) orally.

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Year:  2003        PMID: 14561480     DOI: 10.1016/s0223-5234(03)00144-2

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  4 in total

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3.  Novel heterocyclic 1,3,4-oxadiazole derivatives of fluoroquinolones as a potent antibacterial agent: Synthesis and computational molecular modeling.

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Journal:  Mol Divers       Date:  2021-08-02       Impact factor: 2.943

4.  Catalytic arylsulfonyl radical-triggered 1,5-enyne-bicyclizations and hydrosulfonylation of α,β-conjugates.

Authors:  Zhen-Zhen Chen; Shuai Liu; Wen-Juan Hao; Ge Xu; Shuo Wu; Jiao-Na Miao; Bo Jiang; Shu-Liang Wang; Shu-Jiang Tu; Guigen Li
Journal:  Chem Sci       Date:  2015-11-13       Impact factor: 9.825

  4 in total

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