| Literature DB >> 14552787 |
Yujia Dai1, Yan Guo, Michael L Curtin, Junling Li, Lori J Pease, Jun Guo, Patrick A Marcotte, Keith B Glaser, Steven K Davidsen, Michael R Michaelides.
Abstract
A series of structurally novel HDAC inhibitors, in which a hetero aromatic ring connects the spacer with the hydrophobic group, has been designed and synthesized. These new inhibitors are very potent in in vitro enzymatic assays and display antiproliferation activity against two human cancer cell lines.Entities:
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Year: 2003 PMID： 14552787 DOI： 10.1016/j.bmcl.2003.07.012
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823