Literature DB >> 14528262

Subtleties among subtilases. The structural biology of Kex2 and furin-related prohormone convertases.

Charles Brenner1.   

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Year:  2003        PMID: 14528262      PMCID: PMC1326404          DOI: 10.1038/sj.embor.embor946

Source DB:  PubMed          Journal:  EMBO Rep        ISSN: 1469-221X            Impact factor:   8.807


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  22 in total

Review 1.  Furin at the cutting edge: from protein traffic to embryogenesis and disease.

Authors:  Gary Thomas
Journal:  Nat Rev Mol Cell Biol       Date:  2002-10       Impact factor: 94.444

2.  Direct measurement of acylenzyme hydrolysis demonstrates rate-limiting deacylation in cleavage of physiological sequences by the processing protease Kex2.

Authors:  N C Rockwell; R S Fuller
Journal:  Biochemistry       Date:  2001-03-27       Impact factor: 3.162

3.  The ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation.

Authors:  Eric D Anderson; Sean S Molloy; François Jean; Hao Fei; Satoko Shimamura; Gary Thomas
Journal:  J Biol Chem       Date:  2002-01-17       Impact factor: 5.157

4.  Quantitative characterization of furin specificity. Energetics of substrate discrimination using an internally consistent set of hexapeptidyl methylcoumarinamides.

Authors:  D J Krysan; N C Rockwell; R S Fuller
Journal:  J Biol Chem       Date:  1999-08-13       Impact factor: 5.157

5.  Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor.

Authors:  D Julius; A Brake; L Blair; R Kunisawa; J Thorner
Journal:  Cell       Date:  1984-07       Impact factor: 41.582

6.  2.4 A resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor.

Authors:  Todd Holyoak; Mark A Wilson; Timothy D Fenn; Charles A Kettner; Gregory A Petsko; Robert S Fuller; Dagmar Ringe
Journal:  Biochemistry       Date:  2003-06-10       Impact factor: 3.162

7.  Solution structure of the pro-hormone convertase 1 pro-domain from Mus musculus.

Authors:  Michael A Tangrea; Philip N Bryan; Nese Sari; John Orban
Journal:  J Mol Biol       Date:  2002-07-19       Impact factor: 5.469

Review 8.  Proinsulin and the biosynthesis of insulin.

Authors:  D F Steiner
Journal:  N Engl J Med       Date:  1969-05-15       Impact factor: 91.245

9.  Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase.

Authors:  D Julius; L Blair; A Brake; G Sprague; J Thorner
Journal:  Cell       Date:  1983-03       Impact factor: 41.582

10.  The crystal structure of the proprotein processing proteinase furin explains its stringent specificity.

Authors:  Stefan Henrich; Angus Cameron; Gleb P Bourenkov; Reiner Kiefersauer; Robert Huber; Iris Lindberg; Wolfram Bode; Manuel E Than
Journal:  Nat Struct Biol       Date:  2003-07
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  2 in total

1.  Differential P1 arginine and lysine recognition in the prototypical proprotein convertase Kex2.

Authors:  Joshua L Wheatley; Todd Holyoak
Journal:  Proc Natl Acad Sci U S A       Date:  2007-04-10       Impact factor: 11.205

2.  Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris.

Authors:  Oliver Bader; Yannick Krauke; Bernhard Hube
Journal:  BMC Microbiol       Date:  2008-07-14       Impact factor: 3.605

  2 in total

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