Literature DB >> 14527777

Short term therapy for uncomplicated urinary tract infection today. Clinical outcome upholds the theories.

B Lobel1.   

Abstract

The clinical and bacteriological activity of fosfomycin trometamol (FT) has been compared with several other antibiotics in the treatment of uncomplicated urinary tract infections. A single dose of FT had activity comparable with a 5-day course of trimethoprim in a trial where the causative organism and its sensitivity were unknown. In another trial FT showed better long term eradication compared with a 5-day course of cephalexin and other studies suggested a single dose of FT was comparable with a 7-day course of nitrofurantoin or norfloxacin. There were few important side effects with fosfomycin therapy and it was considered a safe and effective first line treatment in uncomplicated urinary tract infection.

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Year:  2003        PMID： 14527777     DOI： 10.1016/s0924-8579(03)00237-1

Source DB:  PubMed          Journal:  Int J Antimicrob Agents        ISSN： 0924-8579            Impact factor:   5.283


  9 in total

1.  Decreased susceptibility to commonly used antimicrobial agents in bacterial pathogens isolated from urinary tract infections in Rwanda: need for new antimicrobial guidelines.

Authors:  Claude Mambo Muvunyi; Florence Masaisa; Claude Bayingana; Léon Mutesa; André Musemakweri; Grégoire Muhirwa; Geert W Claeys
Journal:  Am J Trop Med Hyg       Date:  2011-06       Impact factor: 2.345

2.  The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase.

Authors:  Mark F Mabanglo; Adrian W R Serohijos; C Dale Poulter
Journal:  Biochemistry       Date:  2012-01-11       Impact factor: 3.162

3.  Stereochemistry of Hydride Transfer by Group III Alcohol Dehydrogenases Involved in Phosphonate Biosynthesis.

Authors:  Spencer C Peck; Seung Young Kim; Bradley S Evans; Wilfred A van der Donk
Journal:  Medchemcomm       Date:  2012-08       Impact factor: 3.597

4.  Biosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe(II)- and NAD(P)H-dependent epoxidation reaction.

Authors:  Feng Yan; Jeffrey W Munos; Pinghua Liu; Hung-wen Liu
Journal:  Biochemistry       Date:  2006-09-26       Impact factor: 3.162

5.  Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis.

Authors:  Svetlana Pakhomova; Sue G Bartlett; Alexandria Augustus; Tomohisa Kuzuyama; Marcia E Newcomer
Journal:  J Biol Chem       Date:  2008-08-12       Impact factor: 5.157

Review 6.  Contemporary management of uncomplicated urinary tract infections.

Authors:  David R P Guay
Journal:  Drugs       Date:  2008       Impact factor: 9.546

7.  Immediate versus conditional treatment of uncomplicated urinary tract infection - a randomized-controlled comparative effectiveness study in general practices.

Authors:  Ildikó Gágyor; Eva Hummers-Pradier; Michael M Kochen; Guido Schmiemann; Karl Wegscheider; Jutta Bleidorn
Journal:  BMC Infect Dis       Date:  2012-06-28       Impact factor: 3.090

8.  Structural basis of regiospecificity of a mononuclear iron enzyme in antibiotic fosfomycin biosynthesis.

Authors:  Danny Yun; Mishtu Dey; Luke J Higgins; Feng Yan; Hung-wen Liu; Catherine L Drennan
Journal:  J Am Chem Soc       Date:  2011-06-30       Impact factor: 15.419

9.  Reducing antibiotic use for uncomplicated urinary tract infection in general practice by treatment with uva-ursi (REGATTA) - a double-blind, randomized, controlled comparative effectiveness trial.

Authors:  Kambiz Afshar; Nina Fleischmann; Guido Schmiemann; Jutta Bleidorn; Eva Hummers-Pradier; Tim Friede; Karl Wegscheider; Michael Moore; Ildikó Gágyor
Journal:  BMC Complement Altern Med       Date:  2018-07-03       Impact factor: 3.659
  9 in total

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