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Literature DB >> 25400901

Stereochemistry of Hydride Transfer by Group III Alcohol Dehydrogenases Involved in Phosphonate Biosynthesis.

Spencer C Peck¹, Seung Young Kim², Bradley S Evans², Wilfred A van der Donk¹.

Abstract

Entities: Chemical Disease Species

Keywords: alcohol dehydrogenase; biosynthesis; fosfomycin; phosphonate; stereochemistry

Year: 2012 PMID： 25400901 PMCID： PMC4231301 DOI： 10.1039/C2MD20009K

Source DB: PubMed Journal: Medchemcomm ISSN： 2040-2503 Impact factor: 3.597

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21 in total

1. Studies on the biosynthesis of fosfomycin. 4. The biosynthetic origin of the methyl group of fosfomycin.

Authors: T Kuzuyama; T Hidaka; K Kamigiri; S Imai; H Seto
Journal: J Antibiot (Tokyo) Date: 1992-11 Impact factor: 2.649

2. New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin.

Authors: Ryan D Woodyer; Gongyong Li; Huimin Zhao; Wilfred A van der Donk
Journal: Chem Commun (Camb) Date: 2006-11-23 Impact factor: 6.222

3. Structure-activity relationships of the phosphonate antibiotic dehydrophos.

Authors: Michael Kuemin; Wilfred A van der Donk
Journal: Chem Commun (Camb) Date: 2010-09-27 Impact factor: 6.222

4. Biosynthesis of rhizocticins, antifungal phosphonate oligopeptides produced by Bacillus subtilis ATCC6633.

Authors: Svetlana A Borisova; Benjamin T Circello; Jun Kai Zhang; Wilfred A van der Donk; William W Metcalf
Journal: Chem Biol Date: 2010-01-29

5. Investigation of the mechanism of phosphinothricin inactivation of Escherichia coli glutamine synthetase using rapid quench kinetic technique.

Authors: L M Abell; J J Villafranca
Journal: Biochemistry Date: 1991-06-25 Impact factor: 3.162

6. The antibiotic dehydrophos is converted to a toxic pyruvate analog by peptide bond cleavage in Salmonella enterica.

Authors: Benjamin T Circello; Charles G Miller; Jin-Hee Lee; Wilfred A van der Donk; William W Metcalf
Journal: Antimicrob Agents Chemother Date: 2011-05-02 Impact factor: 5.191

7. Identification of a variant "Rome clone" of methicillin-resistant Staphylococcus aureus with decreased susceptibility to vancomycin, responsible for an outbreak in an intensive care unit.

Authors: Marco Cassone; Floriana Campanile; Annalisa Pantosti; Mario Venditti; Stefania Stefani
Journal: Microb Drug Resist Date: 2004 Impact factor: 3.431

Stereochemistry of Hydride Transfer by Group III Alcohol Dehydrogenases Involved in Phosphonate Biosynthesis.

1. Studies on the biosynthesis of fosfomycin. 4. The biosynthetic origin of the methyl group of fosfomycin.

2. New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin.

3. Structure-activity relationships of the phosphonate antibiotic dehydrophos.

4. Biosynthesis of rhizocticins, antifungal phosphonate oligopeptides produced by Bacillus subtilis ATCC6633.

5. Investigation of the mechanism of phosphinothricin inactivation of Escherichia coli glutamine synthetase using rapid quench kinetic technique.

6. The antibiotic dehydrophos is converted to a toxic pyruvate analog by peptide bond cleavage in Salmonella enterica.

7. Identification of a variant "Rome clone" of methicillin-resistant Staphylococcus aureus with decreased susceptibility to vancomycin, responsible for an outbreak in an intensive care unit.

8. Production of fosfomycin (phosphonomycin) by Pseudomonas syringae.

9. Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design.

10. On the stereochemistry of 2-hydroxyethylphosphonate dioxygenase.

1. Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation.

2. Biosynthesis of fosfazinomycin is a convergent process.