Literature DB >> 14523919

RNA as a drug target: the case of aminoglycosides.

Quentin Vicens1, Eric Westhof.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 14523919     DOI: 10.1002/cbic.200300684

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


× No keyword cloud information.
  44 in total

1.  Evidence that electrostatic interactions dictate the ligand-induced arrest of RNA global flexibility.

Authors:  Stephen W Pitt; Qi Zhang; Dinshaw J Patel; Hashim M Al-Hashimi
Journal:  Angew Chem Int Ed Engl       Date:  2005-05-30       Impact factor: 15.336

2.  Association of aminoglycosidic antibiotics with the ribosomal A-site studied with Brownian dynamics.

Authors:  Maciej Długosz; Jan M Antosiewicz; Joanna Trylska
Journal:  J Chem Theory Comput       Date:  2008-04       Impact factor: 6.006

3.  Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites.

Authors:  Prabuddha Waduge; Girish C Sati; David Crich; Christine S Chow
Journal:  Bioorg Med Chem       Date:  2019-09-13       Impact factor: 3.641

4.  Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors.

Authors:  Yuefen Zhou; Vlad E Gregor; Zhongxiang Sun; Benjamin K Ayida; Geoffrey C Winters; Douglas Murphy; Klaus B Simonsen; Dionisios Vourloumis; Sarah Fish; Jamie M Froelich; Daniel Wall; Thomas Hermann
Journal:  Antimicrob Agents Chemother       Date:  2005-12       Impact factor: 5.191

Review 5.  Face-time with TAR: Portraits of an HIV-1 RNA with diverse modes of effector recognition relevant for drug discovery.

Authors:  Sai Shashank Chavali; Rachel Bonn-Breach; Joseph E Wedekind
Journal:  J Biol Chem       Date:  2019-05-12       Impact factor: 5.157

6.  Characterizing the relative orientation and dynamics of RNA A-form helices using NMR residual dipolar couplings.

Authors:  Maximillian H Bailor; Catherine Musselman; Alexandar L Hansen; Kush Gulati; Dinshaw J Patel; Hashim M Al-Hashimi
Journal:  Nat Protoc       Date:  2007       Impact factor: 13.491

7.  FRET enabled real time detection of RNA-small molecule binding.

Authors:  Yun Xie; Andrew V Dix; Yitzhak Tor
Journal:  J Am Chem Soc       Date:  2009-12-09       Impact factor: 15.419

8.  Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.

Authors:  Motilal Maiti; Gopinatha Suresh Kumar
Journal:  J Nucleic Acids       Date:  2009-12-15

9.  Defining RNA motif-aminoglycoside interactions via two-dimensional combinatorial screening and structure-activity relationships through sequencing.

Authors:  Sai Pradeep Velagapudi; Matthew D Disney
Journal:  Bioorg Med Chem       Date:  2013-05-07       Impact factor: 3.641

10.  Aminoglycosides: molecular insights on the recognition of RNA and aminoglycoside mimics.

Authors:  Maruthi Chittapragada; Sarah Roberts; Young Wan Ham
Journal:  Perspect Medicin Chem       Date:  2009-04-28
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.