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Literature DB >> 14519191

Tackling an essential problem in functional proteomics of Saccharomyces cerevisiae.

Abstract

Gene inactivation is the cornerstone of functional genetic analysis, but the analysis of essential genes requires conditional inactivation of the gene product. A new study has adapted a simple method for creating conditional alleles to allow large-scale analysis of essential genes in Saccharomyces cerevisiae and has identified a role in DNA replication for a newly identified protein complex.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Fungal Proteins

Year: 2003 PMID： 14519191 PMCID： PMC328445 DOI： 10.1186/gb-2003-4-10-230

Source DB: PubMed Journal: Genome Biol ISSN： 1474-7596 Impact factor: 13.583

19 in total

1. A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication.

Authors: Yumiko Kubota; Youhei Takase; Yasunori Komori; Yoshitami Hashimoto; Toshiaki Arata; Yoichiro Kamimura; Hiroyuki Araki; Haruhiko Takisawa
Journal: Genes Dev Date: 2003-05-01 Impact factor: 11.361

2. Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo.

Authors: Masato Kanemaki; Alberto Sanchez-Diaz; Agnieszka Gambus; Karim Labib
Journal: Nature Date: 2003-05-25 Impact factor: 49.962

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9. Functional profiling of the Saccharomyces cerevisiae genome.

Authors: Guri Giaever; Angela M Chu; Li Ni; Carla Connelly; Linda Riles; Steeve Véronneau; Sally Dow; Ankuta Lucau-Danila; Keith Anderson; Bruno André; Adam P Arkin; Anna Astromoff; Mohamed El-Bakkoury; Rhonda Bangham; Rocio Benito; Sophie Brachat; Stefano Campanaro; Matt Curtiss; Karen Davis; Adam Deutschbauer; Karl-Dieter Entian; Patrick Flaherty; Francoise Foury; David J Garfinkel; Mark Gerstein; Deanna Gotte; Ulrich Güldener; Johannes H Hegemann; Svenja Hempel; Zelek Herman; Daniel F Jaramillo; Diane E Kelly; Steven L Kelly; Peter Kötter; Darlene LaBonte; David C Lamb; Ning Lan; Hong Liang; Hong Liao; Lucy Liu; Chuanyun Luo; Marc Lussier; Rong Mao; Patrice Menard; Siew Loon Ooi; Jose L Revuelta; Christopher J Roberts; Matthias Rose; Petra Ross-Macdonald; Bart Scherens; Greg Schimmack; Brenda Shafer; Daniel D Shoemaker; Sharon Sookhai-Mahadeo; Reginald K Storms; Jeffrey N Strathern; Giorgio Valle; Marleen Voet; Guido Volckaert; Ching-yun Wang; Teresa R Ward; Julie Wilhelmy; Elizabeth A Winzeler; Yonghong Yang; Grace Yen; Elaine Youngman; Kexin Yu; Howard Bussey; Jef D Boeke; Michael Snyder; Peter Philippsen; Ronald W Davis; Mark Johnston
Journal: Nature Date: 2002-07-25 Impact factor: 49.962